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Table 1 Pneumococcal upper respiratory tract isolates analysed in this study. Incidences from 2 years prior to start of vaccination are compared to 3 years after PCV introduction

From: Reduction of Streptococcus pneumoniae in upper respiratory tract cultures and a decreased incidence of related acute otitis media following introduction of childhood pneumococcal conjugate vaccines in a Swedish county

  Prior to PCV introduction (2007/2008) After PCV introduction (2011–2013)
Age (years) Isolates (total number) Incidence per 100,000 (CI 95 %) Isolates (total number) Incidence per 100,000 (CI 95 %)
 ≤ 2 884 2561 (2392–2730) 744 1250 (1161–1341)
3–16 337 229 (205–254) 330 136 (122–151)
17–40 153 51 (43–59) 234 47 (41–52)
41–64 134 45 (37–53) 265 56 (49–62)
65- 58 34 (26–43) 134 45 (37–52)
All ages* 1566 165 (157–173) 1707 110 (104–115)
  1. *p <0.001 for difference in incidence ratio between the two time periods investigated
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