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Table 2 Difference in pneumonia hospitalisation rates in Scotland comparing pre-PCV7 and post-PCV13 periods. With absolute change in hospitalisations by 2012

From: Pneumonia hospitalisations in Scotland following the introduction of pneumococcal conjugate vaccination in young children

Age group

Pneumonia hospitalisations in 2012

Scottish population 2012

Difference in hospitalisation rates per 100,000 population, PrePCV7 vs LatePCV7/PCV13 (n, 95 % CI)

Difference in hospitalisations, PrePCV7 to Late PCV7/PCV13 (%, 95 % CI)a

Expected number of HOSPITALISATIONS from 2000 to 2006 distributionb

Estimated absolute change in number of hospitalisations, 2012 (observed – expected), n, 95 % CI

<2

240

119,275

−87.0 (−107.0, −67.0)

−29.7 (−36.5, −22.8)

349.8

−109.8 (−125.7, −94.0)

2–4

283

176,596

−4.8 (−19.0, 9.0)

−2.8 (−10.5, 5.1)

320.9

−37.9 (−52.7, −23.0)

5–17

262

742,593

2.1 (−1.0, 5.4)

4.9 (−2.3, 12.6)

317.8

−55.8 (−69.9, −42.5)

18–39

783

1,506,987

9.1 (6.4, 11.9)

17.4 (12.2, 22.7)

789.7

−6.7 (−29.3, 15.9)

40–64

3521

1,842,398

70.3 (66.2, 74.4)

62.9 (59.2, 66.6)

2058.0

1463.0 (1424.4, 1500.0)

65–74

3467

507,265

262.0 (247.2, 276.7)

70.4 (66.4, 74.3)

1888.5

1578.5 (1541.4, 1615.5)

75–84

4888

309,244

551.6 (523.4, 579.7)

63.0 (59.8, 66.3)

2705.6

2182.4 (2138.8, 2226.0)

85+

3372

109,242

876.4 (808.7, 944.1)

45.9 (42.4, 49.5)

2085.4

1286.6 (1246.2, 1327.0)

All ages

16,816

5,313,600

110.3 (107.2, 113.3)

59.6 (57.9, 61.2)

9835.5

6980.5 (6895.5, 7060.2)

  1. aAs percentage of 2000–2006 (PrePCV7) data
  2. bDerived from hospitalisation rate from PrePCV7 data applied to the 2012 population figures