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Table 2 Difference in pneumonia hospitalisation rates in Scotland comparing pre-PCV7 and post-PCV13 periods. With absolute change in hospitalisations by 2012

From: Pneumonia hospitalisations in Scotland following the introduction of pneumococcal conjugate vaccination in young children

Age group Pneumonia hospitalisations in 2012 Scottish population 2012 Difference in hospitalisation rates per 100,000 population, PrePCV7 vs LatePCV7/PCV13 (n, 95 % CI) Difference in hospitalisations, PrePCV7 to Late PCV7/PCV13 (%, 95 % CI)a Expected number of HOSPITALISATIONS from 2000 to 2006 distributionb Estimated absolute change in number of hospitalisations, 2012 (observed – expected), n, 95 % CI
<2 240 119,275 −87.0 (−107.0, −67.0) −29.7 (−36.5, −22.8) 349.8 −109.8 (−125.7, −94.0)
2–4 283 176,596 −4.8 (−19.0, 9.0) −2.8 (−10.5, 5.1) 320.9 −37.9 (−52.7, −23.0)
5–17 262 742,593 2.1 (−1.0, 5.4) 4.9 (−2.3, 12.6) 317.8 −55.8 (−69.9, −42.5)
18–39 783 1,506,987 9.1 (6.4, 11.9) 17.4 (12.2, 22.7) 789.7 −6.7 (−29.3, 15.9)
40–64 3521 1,842,398 70.3 (66.2, 74.4) 62.9 (59.2, 66.6) 2058.0 1463.0 (1424.4, 1500.0)
65–74 3467 507,265 262.0 (247.2, 276.7) 70.4 (66.4, 74.3) 1888.5 1578.5 (1541.4, 1615.5)
75–84 4888 309,244 551.6 (523.4, 579.7) 63.0 (59.8, 66.3) 2705.6 2182.4 (2138.8, 2226.0)
85+ 3372 109,242 876.4 (808.7, 944.1) 45.9 (42.4, 49.5) 2085.4 1286.6 (1246.2, 1327.0)
All ages 16,816 5,313,600 110.3 (107.2, 113.3) 59.6 (57.9, 61.2) 9835.5 6980.5 (6895.5, 7060.2)
  1. aAs percentage of 2000–2006 (PrePCV7) data
  2. bDerived from hospitalisation rate from PrePCV7 data applied to the 2012 population figures