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Table 3 Characteristics of currently alive HCV testers by HCV status and birth cohort, Canada, BC-HTC, 1990-2013

From: Twin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepatitis Testers Cohort

  HCV Positive HCV Negative
  <1945 1945-1964 1965-1974 ≥1975 <1945 1945-1964 1965-1974 ≥1975
  N = 3168 N = 33946 N = 11883 N = 6784 N = 95848 N = 310845 N = 209956 N = 371732
  N (%) N (%) N(%) N (%) N (%) N(%) N (%) N (%)
Age at baselinea         
  < 15 0 0 0 438 (6.5) 0 0 0 20289 (5.5)
 15-24 0 0 857 (7.2) 2925 (43.1) 0 0 3591 (1.7) 141735 (38.1)
 25-34 0 2764 (8.1) 6688 (56.3) 3166 (46.7) 0 6369 (2.1) 66420 (31.6) 186558 (50.2)
 35-44 0 14198 (41.8) 4014 (33.8) 255 (3.8) 0 73286 (23.6) 124190 (59.2) 23150 (6.2)
 45-54 425 (13.4) 13116 (38.6) 324 (2.7) 0 3166 (3.3) 144213 (46.4) 15755 (7.5) 0
  ≥ 55 2743 (86.6) 3868 (11.4) 0 0 92682 (96.7) 86977 (28.0) 0 0
Median [IQR] 63 [58-70] 45 [39-50] 32 [28-37] 25 [21–29] 69 [63-75] 50 [44-55] 37 [33-41] 26 [21–30]
Age at 1st test         
  < 15 0 0 0 605 (8.9) 0 0 0 25860 (7)
 15-24 0 0 1205 (10.1) 3830 (56.5) 0 0 7867 (3.8) 181880 (48.9)
 25-34 0 3074 (9.1) 7174 (60.4) 2182 (32.2) 0 12382 (4.0) 96703 (46.1) 151971 (40.9)
 35-44 0 14485 (42.7) 3255 (27.4) 167 (2.5) 0 99462 (32.0) 96915 (46.2) 12021 (3.2)
 45-54 436 (13.8) 12742 (37.5) 249 (2.1) 0 5217 (5.4) 134000 (43.1) 8471 (4.0) 0
  ≥ 55 2732 (86.2) 3645 (10.7) 0 0 90631 (94.6) 65001 (20.9) 0 0
Median [IQR] 63 [58-69] 44 [39-50] 31 [27-36] 22 [18–27] 67 [61-73] 48 [42-53] 35 [30-39] 24 [20–28]
Sex         
 Female 1354 (42.7) 10946 (32.3) 4288 (36.1) 3261 (48.1) 51063 (53.3) 164778 (53.0) 116339 (55.4) 219772 (59.1)
 Male 1809 (57.1) 23000 (67.8) 7594 (63.9) 3523 (51.9) 44657 (46.6) 146061 (47.0) 93615 (44.6) 151954 (40.9)
 Unknown 5 (0.2) 0 0 0 128 (0.1) 6 (0.0) 2 (0.0) 6 (0.0)
Year of diagnosis         
 1990-1994 340 (10.7) 2938 (8.7) 690 (5.8) 99 (1.5) 822 (0.9) 1858 (0.6) 889 (0.4) 344 (0.1)
 1995-1999 1186 (37.4) 12980 (38.2) 3992 (33.6) 857 (12.6) 21815 (22.8) 48746 (15.7) 21003 (10.0) 13299 (3.6)
 2000-2004 703 (22.2) 8333 (24.6) 3163 (26.6) 1650 (24.3) 19159 (20.0) 68035 (21.9) 43673 (20.8) 42021 (11.3)
 2005-2009 555 (17.5) 6004 (17.7) 2588 (21.8) 2257 (33.3) 22709 (23.7) 81513 (26.2) 63756 (30.4) 104908 (28.2)
 2010-2013 384 (12.1) 3691 (10.9) 1450 (12.2) 1921 (28.3) 31343 (32.7) 110693 (35.6) 80635 (38.4) 211160 (56.8)
HIV/AIDS at baseline         
 No/Unknown 3149 (99.4) 33150 (97.7) 11364 (95.6) 6562 (96.7) 95664 (99.8) 308950 (99.4) 208736 (99.4) 370832 (99.8)
 Yes 19 (0.6) 796 (2.3) 519 (4.4) 222 (3.3) 184 (0.2) 1895 (0.6) 1220 (0.6) 900 (0.2)
HIV/AIDS co-infection (ever)         
 No/Unknown 3135 (99.0) 32345 (95.3) 10810 (91.0) 6335 (93.4) 95640 (99.8) 308728 (99.3) 208587 (99.4) 370739 (99.7)
 Yes 33 (1.0) 1601 (4.7) 1073 (9.0) 449 (6.6) 208 (0.2) 2117 (0.7) 1369 (0.7) 993 (0.3)
HBV at baseline         
 No/Unknown 3130 (98.8) 33529 (98.8) 11686 (98.3) 6729 (99.2) 94660 (98.8) 304567 (98.0) 206304 (98.3) 368692 (99.2)
 Yes 38 (1.2) 417 (1.2) 197 (1.7) 55 (0.8) 1188 (1.2) 6278 (2.0) 3652 (1.7) 3040 (0.8)
HBV co-infection (ever)         
 No/Unknown 3075 (97.1) 32643 (96.2) 11330 (95.4) 6658 (98.1) 94059 (98.1) 302130 (97.2) 204856 (97.6) 367414 (98.8)
 Yes 93 (2.9) 1303 (3.8) 553 (4.7) 126 (1.9) 1789 (1.9) 8715 (2.8) 5100 (2.4) 4318 (1.2)
Active TB at baseline         
 No/Unknown 3157 (99.7) 33890 (99.8) 11863 (99.8) 6773 (99.8) 95584 (99.7) 310307 (99.8) 209650 (99.9) 371368 (99.9)
 Yes 11 (0.4) 56 (0.2) 20 (0.2) 11 (0.2) 264 (0.3) 538 (0.2) 306 (0.2) 364 (0.1)
Active TB co-infection (ever)         
 No/Unknown 3149 (99.4) 33783 (99.5) 11808 (99.4) 6752 (99.5) 95494 (99.6) 310145 (99.8) 209558 (99.8) 371276 (99.9)
 Yes 19 (0.6) 163 (0.5) 75 (0.6) 32 (0.5) 354 (0.4) 700 (0.2) 398 (0.2) 456 (0.1)
Material deprivation quintile at baseline         
 Unknown 106 (3.4) 1298 (3.8) 618 (5.2) 469 (6.9) 1199 (1.3) 3720 (1.2) 2671 (1.3) 7183 (1.9)
 Q1 (most privileged) 507 (16.0) 4444 (13.1) 1362 (11.5) 830 (12.2) 18845 (19.7) 65327 (21.0) 48322 (23.0) 81513 (21.9)
 Q2 513 (16.2) 5404 (15.9) 1636 (13.8) 936 (13.8) 18165 (19.0) 60803 (19.6) 39355 (18.7) 69264 (18.6)
 Q3 533 (16.8) 6114 (18) 1926 (16.2) 1065 (15.7) 19060 (19.9) 61814 (19.9) 40022 (19.1) 71369 (19.2)
 Q4 660 (20.8) 7365 (21.7) 2691 (22.7) 1514 (22.3) 20032 (20.9) 61824 (19.9) 40792 (19.4) 74468 (20.0)
 Q5 (most deprived) 849 (26.8) 9321 (27.5) 3650 (30.7) 1970 (29.0) 18547 (19.4) 57357 (18.5) 38794 (18.5) 67935 (18.3)
Social deprivation quintile at baseline         
 Unknown 106 (3.4) 1298 (3.8) 618 (5.2) 469 (6.9) 1199 (1.3) 3720 (1.2) 2671 (1.3) 7183 (1.9)
 Q1 (most privileged) 557 (17.6) 3477 (10.2) 1081 (9.1) 741 (10.9) 17348 (18.1) 57695 (18.6) 36550 (17.4) 68621 (18.5)
 Q2 513 (16.2) 4335 (12.8) 1238 (10.4) 794 (11.7) 17802 (18.6) 56839 (18.3) 36109 (17.2) 64348 (17.3)
 Q3 516 (16.3) 5802 (17.1) 1790 (15.1) 989 (14.6) 17342 (18.1) 56864 (18.3) 36204 (17.2) 65305 (17.6)
 Q4 606 (19.1) 7152 (21.1) 2380 (20.0) 1257 (18.5) 19201 (20.0) 62437 (20.1) 42960 (20.5) 76953 (20.7)
 Q5 (most deprived) 870 (27.5) 11882 (35.0) 4776 (40.2) 2534 (37.4) 22956 (24.0) 73290 (23.6) 55462 (26.4) 89322 (24.0)
Mental illness at baselineb         
 No/Unknown 2768 (89.8) 28051 (85.0) 9468 (81.9) 4942 (79.5) 75892 (90.3) 230429 (85.6) 160387 (87.7) 262690 (89.8)
 Yes 316 (10.2) 4956 (15.0) 2087 (18.1) 1277 (20.5) 8130 (9.7) 38636 (14.4) 22397 (12.3) 29891 (10.2)
Mental illness 3yr pre- baselineb         
 No/Unknown 2908 (94.3) 30114 (91.2) 10261 (88.8) 5478 (88.1) 80387 (95.7) 251001 (93.3) 172141 (94.2) 277513 (94.8)
 Yes 176 (5.7) 2893 (8.8) 1294 (11.2) 741 (11.9) 3635 (4.3) 18064 (6.7) 10643 (5.8) 15068 (5.2)
Illicit drug use at baselineb         
 No/Unknown 2763 (89.6) 22649 (68.6) 6220 (53.8) 3256 (52.4) 81535 (97.0) 249677 (92.8) 167729 (91.8) 271558 (92.8)
 Yes 321 (10.4) 10358 (31.4) 5335 (46.2) 2963 (47.6) 2487 (3.0) 19388 (7.2) 15055 (8.2) 21023 (7.2)
Illicit drug use 3yr pre- baselineb         
 No/Unknown 2870 (93.1) 25193 (76.3) 7090 (61.4) 3557 (57.2) 83133 (98.9) 259681 (96.5) 174045 (95.2) 278466 (95.2)
 Yes 214 (6.9) 7814 (23.7) 4465 (38.6) 2662 (42.8) 889 (1.1) 9384 (3.5) 8739 (4.8) 14115 (4.8)
Problematic alcohol use at baselineb         
 No/Unknown 2724 (88.3) 25720 (77.9) 8780 (76.0) 4933 (79.3) 79838 (95.0) 248826 (92.5) 171200 (93.7) 277407 (94.8)
 Yes 360 (11.7) 7287 (22.1) 2775 (24.0) 1286 (20.7) 4184 (5.0) 20239 (7.5) 11584 (6.3) 15174 (5.2)
Problematic alcohol use 3yr pre-baselineb         
 No/Unknown 2870 (93.1) 28620 (86.7) 9874 (85.5) 5421 (87.2) 81897 (97.5) 258911 (96.2) 177020 (96.8) 284664 (97.3)
 Yes 214 (6.9) 4387 (13.3) 1681 (14.5) 798 (12.8) 2125 (2.5) 10154 (3.8) 5764 (3.2) 7917 (2.7)
  1. aBaseline is defined as date of diagnosis (i.e. first HCV positive test or case report) for HCV positive individuals, and date of last negative test result for HCV negative individuals
  2. bMental health, drug misuse, alcohol misuse data was available up to 2012