Fig. 2

Adjusted average monthly rates of antibiotics, proton pump inhibitors and their co-administration over time. Monthly rates of antibiotics, PPIs, and the co-administration of antibiotics and PPIs are presented as adjusted days of therapy (DOT) per 100 inpatient days whereby one DOT represents the administration of a single medication on a given day irrespective of dosing frequency or strength. P values for each time period comparison (baseline-alert, alert-stewardship, and baseline-stewardship) are included. PPI = proton pump inhibitor