Predisposing Factor | No. of episodes (%) | Died (No.) | CFR (%) | RR of death (95Â % CI) | No. of Pat. with Factorc | Incidenced (No./100,000/y.) | RR to get IPD (95Â % CI) |
---|---|---|---|---|---|---|---|
Cardiovascular disease | 720 (24) | 126 | 18 | 2.35 (1.90–2.92)a |  |  |  |
Pulmonary disease | 531 (18) | 51 | 10 | 0.97 (0.73–1.29) |  |  |  |
- COPD | 307 (10) | 38 | 12 | 1.29 (0.94–1.78) | 49,000 | 48 | 3.52 (3.12–3.98)a |
- Asthma | 145 (5) | 4 | 3 | 0.27 (0.10–0.71)b | 130,000 | 9 | 0.57 (0.48–0.68)b |
Malignancy | 485 (16) | 87 | 18 | 2.16 (1.71–2.72)a | 72,000 | 52 | 4.09 (3.69–4.52)a |
- Haematological | 257 (9) | 35 | 14 | 1.43 (1.03–1.99)a | 4900 | 403 | 29.16 (25.66–33.13)a |
- - Myeloma | 128 (4) | 23 | 18 | 1.89 (1.28–2.78)a | 440 | 2238 | 154.37 (132.51–179.84)a |
- - Chronic Lymphatic Leukemia | 53 (2) | 4 | 8 | 0.76 (0.29–1.96) | 950 | 429 | 28.86 (22.13–37.63)a |
- Solid tumors | 158 (5) | 50 | 32 | 3.66 (2.82–4.73)a | 67,200 | 18 | 1.26 (1.07–1.48)a |
- - Lung | 52 (2) | 21 | 40 | 4.33 (3.05–6.13)a | 1200 | 333 | 22.40 (17.11–29.33)a |
- - Breast | 23 (1) | 0 | 0 | n.a. | 14,600 | 12 | 0.81 (0.53–1.22) |
- - Colon | 22 (1) | 4 | 18 | 1.85 (0.76–4.53) | 4600 | 37 | 2.44 (1.61–3.72)a |
- - Prostate | 46 (2) | 5 | 11 | 1.10 (0.48–2.54) | 11,900 | 30 | 1.99 (1.49–2.67)a |
Diabetes mellitus | 336 (11) | 36 | 11 | 1.10 (0.79–1.52) | 60,500 | 43 | 3.18 (2.83–3.57)a |
Autoimmune Disease | 227 (8) | 26 | 11 | 1.17 (0.80–1.72) |  |  |  |
- Rheumatoid Arthritis | 80 (3) | 8 | 10 | 1.01 (0.52–1.97) | 8500 | 72 | 4.91 (3.93–6.14)a |
- Polymyalgia rheumatica | 44 (1) | 7 | 16 | 1.63 (0.82–3.23) |  |  |  |
- Systemic Lupus Erythematosus | 23 (1) | 2 | 9 | 0.88 (0.23–3.32) | 830 | 213 | 14.19 (9.64–21.28)a |
Liver disease | 99 (3) | 11 | 11 | 1.13 (0.64–1.99) |  |  |  |
Renal disease | 109 (4) | 17 | 16 | 1.61 (1.03–2.53)a |  |  |  |
- Haemodialysis | 17 (1) | 5 | 29 | 3.01 (1.43–6.34)a | 385 | 340 | 22.56 (14.15–35.98)a |
- Peritoneal dialysis | 5 (0) | 1 | 20 | 2.03 (0.35–11.75) | 137 | 281 | 18.57 (7.85–43.96)a |
Immune deficiency | 93 (3) | 7 | 8 | 0.76 (0.37–1.55) |  |  |  |
- HIV | 13 (0) | 1 | 8 | 0.78 (0.12–5.13) | 407 | 246 | 16.30 (9.53–27.87)a |
- Bone Marrow Transplant | 20 (1) | 2 | 10 | 1.01 (0.27–3.79) |  |  |  |
- Hypogammaglobulinemia | 22 (1) | 0 | 0 | Â | Â | Â | Â |
- MGUS | 26 (1) | 2 | 8 | 0.59 (0.16–2.26) | 17,000 | 12 | 0.81 (0.56–1.19) |
Immunosuppressive treatment | 279 (9) | 36 | 13 | 1.35 (0.97–1.87) |  |  |  |
Asplenia | 41 (1) | 5 | 12 | 1.24 (0.54–2.84) | 1500 | 210 | 14.08 (10.38–19.10)a |
Alcohol Dependency | 220 (7) | 23 | 10 | 1.06 (0.71–1.59) |  |  |  |
≥ 1 predisposing factore | 1994 (67) | 257 | 12.9 | 3.43 (2.45–4.81)a |  |  |  |
All Episodes | 2977 (100) | 294 | 9.9 | Â | 1,512,233 | 15 | Â |