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Table 1 Characteristics critically ill HIV patients coinfected with TB (laboratory-confirmed) diagnosis, including the characteristics of Tuberculosis (TB) presentation and treatment and the prevalence of organ dysfunctions at ICU admission (N = 44)

From: Six-month survival of critically ill patients with HIV-related disease and tuberculosis: a retrospective study

  HIV/AIDS and Tuberculosis (N = 44) Survivors (N = 21) Non-survivors (N = 23) p value
Age (years) 34 (19.25–44.5) 32 (27–42.5) 36 (30–46) 0.15
Gender (male) 31 (70 %) 14 (67 %) 17 (74 %) 0.74
Nadir CD4a 54 (17–96) 73 (30–177) 23 (14–84) 0.04
Viral load (×103 copies/mm3)b 113,637 (2,995–365,663) 35,149 (212.3–300,184) 169,133 (35,405–419,382) 0.13
Length of time since HIV diagnosis (months) 5 (1–60) 1 (1–16) 28 (1–72) 0.03
cART use while in the ICU 17 (38.6 %) 10 (48 %) 7 (30 %) 0.35
Mechanical ventilation use on ICU day 1 21 (48 %) 8 (42 %) 13 (52 %) 0.56
Vasoactive drug use on ICU day 1 12 (26 %) 5 (24 %) 7 (27 %) 0.99
SAPS II score (points) 47 (37–55) 48 (37–57) 46 (38–54) 0.27
SOFA score on day 1 (points) 4 (1–8) 1 (0–7) 5 (2–8) 0.08
Isolated TB pulmonary presentation 22 (50 %) 10 (48 %) 12 (52 %) 1.00
Disseminated TB presentation 22 (50 %) 11 (52 %) 11 (48 %) 1.00
TB treatment before ICU admission 25 (57 %) 11 (52 %) 14 (61 %) 0.76
TB treatment     
 - only by enteral drugs 16 (36 %) 10 (48 %) 6 (26 %) 0.21
 - adding intravenous drugs 28 (64 %) 11 (52 %) 17 (74 %)  
TB treatment: Δ ICU admission 0 (-5–+21) -5 (-23–+2) -5 (-21–0) 0.09
TB treatment before ICU 25 (57 %) 11 (52.4 %) 14 (61 %) 0.76
Organ Dysfunctions     
 Cardiovascular 18 (41 %) 7 (33.3 %) 11 (48 %) 0.37
 Respiratory 15 (34 %) 5 (24 %) 10 (43 %) 0.21
 Renal 14 (32 %) 5 (24 %) 9 (39 %) 0.34
 Neurological 13 (29 %) 3 (14 %) 10 (43 %) 0.04
 Hepatic 9 (20 %) 5 (24 %) 4 (17 %) 0.71
 Hematological 9 (20 %) 3 (14 %) 6 (26 %) 0.46
  1. Comparison between survivors and nonsurvivors for six-month survival. Results were expressed as the median and the interquartile interval
  2. adata available for 39 patients
  3. bdata available for 35 patients
  4. Δ:time from starting TB treatment and beeing admitted to ICU. Negative (-) mean prior to ICU admission and positive (+) means after ICU admission