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Table 3 Characteristics of non-pregnancy associated cases of listeriosis influencing time between onset of illness and collection of specimen

From: Factors influencing the time between onset of illness and specimen collection in the diagnosis of non-pregnancy associated listeriosis in England and Wales

Patient characteristics

Number of casesa(%) (N = 1210)

Median number of days between onset of symptoms and collection of specimen (IQR) (in days)

Change in time difference between onset of symptoms and collection of specimen

Unadjusted (95 % C1)

(in days)

P-value of LRTb

Adjusted (95 % CI) (in days)

No of observations - 886

P-value of LRTb

Age

 0–9 years

7 (0.6)

2 (1 to 18)

0

0.18

0

0.08

 10–29 years

32 (2.6)

2 (0 to 5)

−2.5 (−11.6 to 6.5)

 

−3.1 (−15.3 to 9.2)

 

 30–49 years

103 (8.5)

2 (0 to 5)

−1.8 (−10.7 to 7.1)

 

−4.5 (−16.6 to 7.5)

 

 50–69 years

448 (37.0)

2 (0 to 5)

−2.9 (−11.7 to 5.8)

 

−4.4 (−16.3 to 7.5)

 

 70+ years

620 (51.2)

1 (0 to 4)

−2.5 (−11.2 to 6.2)

 

−3.6 (−15.6 to 8.2)

 

Gender

 Females

537 (44.4)

2 (0 to 4)

0

0.77

0

0.27

 Males

673 (55.6)

1 (0 to 4)

+0.1 (−0.8 to 0.9)

 

+0.3 (−0.5 to 1.2)

 

Ethnicity

 White British

1057 (87.4)

1 (0 to 4)

0

0.24

0

0.11

 Others

153 (12.6)

2 (1 to 5)

+0.5 (−0.9 to 1.9)

 

+0.8 (−0.6 to 2.3)

 

Deprivation

 1 (least)

224 (18.6)

1.5 (0 to 4)

0

0.05

0

0.02

 2

235 (19.5)

2 (1 to 4)

+0.2 (−0.9 to 1.5)

 

−0.1 (−1.2 to 1.0)

 

 3

229 (19.1)

2 (0 to 5)

+1.1 (−0.3 to 2.4)

 

+1.2 (−0.2 to 2.7)

 

 4

260 (21.6)

1 (0 to 4)

+1.1 (−0.2 to 2.5)

 

+1.0 (−0.3 to 2.3)

 

 5 (most)

255 (21.2)

2 (0 to 5)

+0.7 (−0.5 to 2.0)

 

+0.7 (−0.5 to 2.0)

 

 Unknown

7

     

Serogroup

 1/2a

341 (32.8)

1 (0 to 4)

0

<0.001

0

<0.003

 1/2b

97 (9.3)

1 (0 to 3)

−1.3 (−2.7 to −0.6)

 

−1.5 (−2.7 to −0.3)

 

 1/2c

36 (3.5)

1 (0 to 4.5)

−0.9 (−3.0 to 1.2)

 

−0.6 (−2.5 to 1.2)

 

 4

566 (54.4)

2 (0 to 5)

+0.6 (−0.4 to 1.6)

 

+0.2 (−0.7 to 1.2)

 

 Unknown

170

     

Underlying condition

 Absent

168 (15.1)

2 (1 to 5)

0

<0.002

0

0.001

 Present

942 (84.9)

1 (0 to 4)

−1.3 (−2.8 to 0.2)

 

−1.5 (−3.1 to −0.03)

 

 Unknown

100

     

Presenting illness

 Other illness

91 (8.1)

2 (0 to 6)

0

<0.001

0

<0.001

 Gastroenteritis

46 (4.1)

1 (0 to 6)

+0.8 (−2.8 to 4.5)

 

+.2.7 (−1.5 to 7.1)

 

 Meningitis

140 (12.4)

2 (1 to 5)

−0.8 (−3.1 to 1.6)

 

−0.7 (−3.1 to 1.6)

 

 Septicaemia

618 (54.8)

1 (0 to 4)

−1.5 (−3.6 to 0.4)

 

−0.8 (−2.8 to 1.2)

 

 Septicaemia and Gastroenteritis

83 (7.4)

2 (0 to 6)

+0.1 (−2.7 to 2.9)

 

+0.4 (−2.2 to 3.2)

 

 Meningitis and Septicaemia

143 (12.7)

2 (0 to 3)

−2.4 (−4.5 to −0.2)

 

−1.7 (−3.8 to 0.4)

 

 Meningitis and Septicaemia and Gastroenteritis

7 (0.6)

6 (4 to 10)

+1.2 (−7.4 to 9.9)

 

+2.2 (−6.5 to 11.1)

 
 

82

     

Survival

 Alive

768 (66.7)

2 (0 to 4)

0

0.52

0

0.76

 Died

383 (33.3)

1 (0 to 4)

−0.2 (−1.2 to 0.8)

 

+0.1 (−0.8 to 1.0)

 

 Unknown

59

     
  1. aData available as Additional file 1: Data of non-pregnancy associated listeriosis
  2. bLikelihood ratio test