Sending repeat cultures: is there a role in the management of bacteremic episodes? (SCRIBE study)

BMC Infectious Diseases

Table 5 Nested case control analysis: multivariate analysis to identify predictors of persistent bacteremia in patients with repeat cultures

Variable	Odds ratio	95 % CI	P value
Sex
Male	2.59	1.28–5.25	0.008
Female^a	1.00	1.00	1.00
Admitting service
Medical in-patient	2.80	1.34–5.84	0.006
Heme-onc in-patient	1.21	0.44–3.33	0.71
Surgical in-patient^a	1.00	1.00	1.00
Organism
S. aureus	4.49	1.88–10.73	<0.001
Other Gram-positive bacteria	0.80	0.35–1.82	0.59
Anaerobes	0.96	0.15–6.38	0.97
All Gram-negative bacteria^a	1.00	1.00	1.00
Source of bacteremia
Endovascular	7.66	2.30–25.48	<0.001
Epidural abscess/discitis	26.99	1.91–391.08	0.015
Other extravascular source	3.02	0.97–9.41	0.057
Unknown source^a	1.00	1.00	1.00

NOTE: Multivariable logistic regression was performed including all variables associated with persistent bacteremia in bivariate analyses in the nested case control analysis, with stepwise backward selection for variable reduction until all retained variables were statistically significant at p-value threshold <0.05 (statistically significant values are bolded). Referent categories are indicated with ‘^a’. Heme-onc hematology-oncology in-patient ward

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