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Table 2 Pharmacokinetic parameters of China-made Peramivir

From: Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experiment

Parameters

 

Control mice

Virus-infected mice

AUC(0-∞)

μg/L/h

37307.80

38518.79

MRT(0-∞)

h

0.38

0.536

t1/2

h

0.289

0.341

CL

L/h/kg

1.662

1.61

V

L/kg

0.693

0.793

Cmax

μg

48037.54

47224.08

  1. AUC area under curve, MRT mean retention time, t 1/2 half a life, CL clearance, V volume of distribution, C max maximum concentration