Variable | Total no. | No. with late-appearing anaemia | OR (95Â % CI) | P value | AOR (95Â % CI) | P value |
---|---|---|---|---|---|---|
Gender | Â | Â | Â | Â | Â | Â |
 Female | 270 | 37 | 1 |  |  |  |
 Male | 339 | 47 | 1.0(0.6–1.6) | 0.95 | - | - |
Age (years) | Â | Â | Â | Â | Â | Â |
  ≥ 3 | 556 | 65 | 1 |  | 1 |  |
  < 3 | 53 | 19 | 4.2(2.3–7.8) | 0.000004 | 2.6 (1.3–5.2) | 0.005 |
Duration of illness (days) | Â | Â | Â | Â | Â | Â |
  ≤ 2 days | 200 | 28 | 1 |  |  |  |
  > 2 days | 343 | 53 | 1.1(0.7–1.8) | 0.81 | - | - |
Enrolment body temperature | Â | Â | Â | Â | Â | Â |
  ≤ 37.4 °C | 164 | 19 | 1 |  |  |  |
  > 37.4 °C | 445 | 65 | 1.3 (0.8–2.3) | 0.41 | - | - |
Fever on day 1 | Â | Â | Â | Â | Â | Â |
 Absent | 568 | 70 | 1 |  | 1 |  |
 Present | 41 | 14 | 3.7(1.8–7.4) | 0.0002 | 3.8 (1.8–8.2) | <0.0001 |
Haematocrit at presentation (day 0) | Â | Â | Â | Â | Â | Â |
  ≥ 25 % | 554 | 65 | 1 |  | 1 |  |
  < 25 % | 55 | 19 | 4.0(2.2–7.3) | 0.000008 | 2.2(1.3–3.7) | 0.003 |
Haematocrit on day1 | Â | Â | Â | Â | Â | Â |
  ≥ 30 % | 421 | 40 | 1 |  | 1 |  |
  < 30 % | 188 | 44 | 2.9(1.8–4.7) | 0.000009 | 2.1(1.0–4.3) | 0.04 |
Parasitaemia (μL−1) |  |  |  |  |  |  |
  ≤ 50,000 | 320 | 34 | 1 |  |  |  |
  > 50,000 | 289 | 50 | 0.7(0.5–1.2) | 0.21 |  |  |
Parasite reduction ratio on day1 | Â | Â | Â | Â | Â | Â |
  ≤ 10,000 | 443 | 57 | 1 |  |  |  |
  > 10,000 | 166 | 27 | 0.8 (0.5–1.3) | 0.34 | - | - |
Parasite reduction ratio on day2 | Â | Â | Â | Â | Â | Â |
 ≤ 10,000 | 532 | 67 | 1 |  | 1 |  |
  > 10,000 | 77 | 17 | 2.0 (1.1–3.6) | 0.038 | 2.1(1.1–3.9) | 0.03 |
Liver enlargement | Â | Â | Â | Â | Â | Â |
 Absent | 511 | 70 | 1 |  |  |  |
 Present | 98 | 14 | 1.0(0.6–1.9) | 0.98 |  |  |
Spleen enlargement | Â | Â | Â | Â | Â | Â |
 Absent | 535 | 67 | 1 |  | 1 |  |
 Present | 64 | 17 | 2.4(1.3–4.3) | 0.008 | 2.0(1.1–3.9) | <0.0001 |
Parasite clearance time | Â | Â | Â | Â | Â | Â |
  < 1 day | 506 | 73 | 1 |  |  |  |
  > 1 day | 103 | 11 | 0.7(0.4–1.4) | 0.40 | - | - |
Fever clearance time | Â | Â | Â | Â | Â | Â |
  < 1 day | 574 | 75 | 1 |  |  |  |
  > 1 day | 35 | 9 | 1.9(0.9–4.3) | 0.13 |  |  |
FIH/1000 asexual parasite cpba | Â | Â | Â | Â | Â | Â |
  ≥ 0.05 | 133 | 28 | 1 |  |  |  |
  < 0.05 | 258 | 39 | 0.7(0.4–1.2) | 0.27 |  |  |
Year of enrolment | Â | Â | Â | Â | Â | Â |
  < 2010 | 242 | 33 | 1 |  |  |  |
  ≥ 2010 | 367 | 51 | 1.0(0.6–1.6) | 0.93 |  |  |