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Table 3 Outcome analysis comparing β-lactam versus vancomycin group. Variables were adjusted for predefined confounding variables, including age, sex, age-adjusted Charlson-comorbidity index, Pitt bacteremia score, infectious diseases consultation, infective endocarditis and time to receipt of empiric antibiotics. Duration of bacteremia was further adjusted for surgical source control

From: Comparison of outcomes in patients with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia who are treated with β-lactam vs vancomycin empiric therapy: a retrospective cohort study

Outcomes

Crude OR (95 % CI)

P-value

Adjusted OR (95 % CI)

P-value

28-day mortality

0.88 (0.44–1.78)

0.72

1.14 (0.49–2.64)

0.76

90-day mortality

0.75 (0.43–1.32)

0.32

1.01 (0.51–2.02)

0.97

Recurrent infection at 6 months

0.87 (0.31–2.45)

0.79

1.27 (0.39–4.11)

0.69

 

Ratio of Mean (95 % CI)

P-value

Adjusted Ratio of Mean (95 % CI)

P-value

Duration of bacteremia

0.92 (0.78–1.07)

0.27

0.94 (0.79–1.11)

0.44

Hospital length-of-stay

0.96 (0.81–1.14)

0.65

0.95 (0.80–1.14)

0.60

  1. Abbreviations: OR odds ratio, CI confidence interval