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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Paracoccidioides brasiliensis infection promotes thymic disarrangement and premature egress of mature lymphocytes expressing prohibitive TCRs

Fig. 4

Expression of “prohibited” TCRVβ segments in T cells from spleens during acute P. brasiliensis infection. Male Balb/c mice (n = 5 mice/group) were injected i.p. with Pb cells. Seven days later, spleens were analyzed for expression of TCRVβ5 and Vβ12 segments in T cells from infected and control mice. Increased expression of TCRVβ5 and Vβ12 segments in (a) CD4 and TCRVβ12 segment in (b) CD8 T lymphocyte in spleens of infected mice. Data was analyzed by Student t test. Values of p ≤ 0,05 (*),p ≤ 0,01 (**) were considered statistically significant. Results are expressed by Mean ± SEM. Representative data from three independent experiments with similar results

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