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Table 3 Comparative analysis of indicators for bacterial vaginosis assessed with the three molecular methods 16S rRNA amplicon sequencing, microarray, and IS profiling

From: Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity

Cl. TCMID BV Nugent score Gini Simpson index Relative abundance genus Lactobacillus Relative abundance L. crispatus Relative abundance L. iners
     Seq Micr IS-pro Seq Micr IS-pro Seq Micr IS-pro Seq Micr IS-pro
I 101 BV- 0 0.03 0.73 0.69 0.98 0.89 0.98 0.00 0.00 0.02 0.98 0.46 0.95
I 103 BV- 0 0.12 0.82 0.34 0.99 0.91 0.92 0.00 0.00 0.00 0.93 0.53 0.92
I 113 BV- 2 0.09 0.87 0.80 0.97 0.49 0.95 0.00 0.00 0.01 0.95 0.22 0.69
II 111 BV- 2 0.05 0.61 0.60 0.97 0.73 0.92 0.97 0.53 0.92 0.00 0.00 0.00
II 102 BV- 0 0.05 0.67 0.67 0.99 0.98 0.97 0.97 0.69 0.89 0.01 0.00 0.06
II 112 BV- 2 0.01 0.74 0.67 1.00 1.00 0.97 0.99 0.65 0.94 0.00 0.00 0.00
III 126 BV+ 9 0.60 0.78 0.81 0.05 0.00 0.32 0.00 0.00 0.00 0.04 0.00 0.32
III 135 BV+ 10 0.77 0.89 0.86 0.05 0.01 0.18 0.00 0.00 0.00 0.05 0.01 0.18
IV 134 BV+ 10 0.44 0.91 0.97 0.01 0.00 0.10 0.00 0.00 0.00 0.01 0.00 0.10
IV 136 BV+ 10 0.68 0.85 0.87 0.13 0.11 0.26 0.00 0.00 0.00 0.13 0.03 0.26
V 117 BV+ 8 0.82 0.82 0.86 0.01 0.00 0.04 0.00 0.00 0.00 0.01 0.00 0.04
V 118 BV+ 8 0.86 0.87 0.85 0.02 0.00 0.16 0.00 0.00 0.00 0.02 0.00 0.16
V 120 BV+ 8 0.76 0.87 0.83 0.05 0.00 0.13 0.00 0.00 0.00 0.05 0.00 0.13
  1. The indicators, Gini-Simpson index, abundance of the genus Lactobacillus, and L. crispatus, and L. iners have been shown for representatives of each of the 5 clusters (a total of 13 samples). The Gini-Simpson index represents the species diversity (0 = low diversity, 1 = high diversity), the abundance of the genus Lactobacillus, and L. crispatus, and L. iners is shown as a relative abundance between 0 and 1