Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity

BMC Infectious Diseases

Table 3 Comparative analysis of indicators for bacterial vaginosis assessed with the three molecular methods 16S rRNA amplicon sequencing, microarray, and IS profiling

Cl.	TCMID	BV	Nugent score	Gini Simpson index			Relative abundance genus Lactobacillus			Relative abundance L. crispatus			Relative abundance L. iners
				Seq	Micr	IS-pro	Seq	Micr	IS-pro	Seq	Micr	IS-pro	Seq	Micr	IS-pro
I	101	BV-	0	0.03	0.73	0.69	0.98	0.89	0.98	0.00	0.00	0.02	0.98	0.46	0.95
I	103	BV-	0	0.12	0.82	0.34	0.99	0.91	0.92	0.00	0.00	0.00	0.93	0.53	0.92
I	113	BV-	2	0.09	0.87	0.80	0.97	0.49	0.95	0.00	0.00	0.01	0.95	0.22	0.69
II	111	BV-	2	0.05	0.61	0.60	0.97	0.73	0.92	0.97	0.53	0.92	0.00	0.00	0.00
II	102	BV-	0	0.05	0.67	0.67	0.99	0.98	0.97	0.97	0.69	0.89	0.01	0.00	0.06
II	112	BV-	2	0.01	0.74	0.67	1.00	1.00	0.97	0.99	0.65	0.94	0.00	0.00	0.00
III	126	BV+	9	0.60	0.78	0.81	0.05	0.00	0.32	0.00	0.00	0.00	0.04	0.00	0.32
III	135	BV+	10	0.77	0.89	0.86	0.05	0.01	0.18	0.00	0.00	0.00	0.05	0.01	0.18
IV	134	BV+	10	0.44	0.91	0.97	0.01	0.00	0.10	0.00	0.00	0.00	0.01	0.00	0.10
IV	136	BV+	10	0.68	0.85	0.87	0.13	0.11	0.26	0.00	0.00	0.00	0.13	0.03	0.26
V	117	BV+	8	0.82	0.82	0.86	0.01	0.00	0.04	0.00	0.00	0.00	0.01	0.00	0.04
V	118	BV+	8	0.86	0.87	0.85	0.02	0.00	0.16	0.00	0.00	0.00	0.02	0.00	0.16
V	120	BV+	8	0.76	0.87	0.83	0.05	0.00	0.13	0.00	0.00	0.00	0.05	0.00	0.13

The indicators, Gini-Simpson index, abundance of the genus Lactobacillus, and L. crispatus, and L. iners have been shown for representatives of each of the 5 clusters (a total of 13 samples). The Gini-Simpson index represents the species diversity (0 = low diversity, 1 = high diversity), the abundance of the genus Lactobacillus, and L. crispatus, and L. iners is shown as a relative abundance between 0 and 1

ISSN: 1471-2334