Table 1 Characteristics of the study population
Untreated HIV-infected patients | |
|---|---|
Characteristics | Total sample (n = 62) |
Age (years, range) | 39 (24–68) |
Gender (male, n(%)) | 32 (52) |
CD4+ cell count (cells/μL) | 190 (98–530) |
HIV RNA blood (copies/mL) | 39587 (8799–172541) |
HIV RNA CSF (copies/mL) | 4690 (749–28150) |
Leucocytes CSF (cells/μL) | 5 (1–9) |
Serum albumin (g/L) | 39 (36–42) |
CSF albumin (mg/L) | 165 (136–243) |
Albumin ratio | 3.5 (4.1–5.9) |
Mode of transmission (n (%)): | |
Heterosexual | 49 (79) |
MSM | 11 (18) |
IV drug users | 2 (3) |
AIDS defining diseases (n (%)): | |
Pneumocystis jirovecii pneumonia | 1 (2) |
Wasting syndrome | 2 (3) |
Tuberculosis | 1 (2) |
Biomarkers | |
LPS plasma (pg/mL) | 102 (78–121) |
sCD14 plasma (ng/mL) | 2382 (1941–3111) |
sCD14 CSF (ng/mL) | 222 (161–373) |
Neopterin plasma (nmol/L) | 12 (9–23) |
Neopterin CSF (nmol/L) | 15 (8–22) |
NFL CSF (ng/L) | 410 (250–635) |