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Table 5 Comparison of the number of CDI episodes in 2009 in the Medicare data according to the extent of information used to identify CDI

From: The burden of clostridium difficile infection: estimates of the incidence of CDI from U.S. Administrative databases

   Source of information from medicare files
Type of CDI Definition of CDI Complete inpatient + outpatient Inpatient only (comparable to SID) Inpatient-unlinked (comparable to NIS)
 # hospital stays 488,344 488,344 522,921
 Total Inpatient CDI episodes 5,576 6,276 8,108
 Inpatient CDI Episodes Primary discharge diagnosis) 1,464 1,690 2,084
Admission diagnosis 487 584 824
Secondary discharge diagnosis 3,625 4,002 5,200
 Outpatient CDI episodes 4,076 N/A N/A
 Total CDI episodes 9,652 6,276 8,108
Categorization of CDI Episodes (% of episodes)
 Hospital-Onset 3,223 (33.4) 3,765 (60.0) 4,769 (58.8)
 Other Healthcare Facility-Onset 2,425 (25.1) N/A N/A
 Community-Onset Healthcare Facility–associated 1,258 (13.0) 938 (14.9) N/A
 Community-associated CDI 2,185 (22.6) 1,032 (16.4) 3,339 (41.2)
 Indeterminate 561 (5.8) 541 (8.6) N/A
Rate of CDI Episodes
 Rate of CDI/100,000 person-years 677 440 553a
 Rate of hospital onset CDI/10,000 pt. days 9.8 11.4 14.1
 Prevalence of CDI at admission/1,000 hospitalizations 5.4 5.3 6.5
 Rate of healthcare facility-associated CDI/10,000 pt. days 12.5 14.2 14.1
  1. aper 100,000 population aged 65 and older from the 2010 census