From: Treatment outcomes of reduced-dose intravitreal ganciclovir for cytomegalovirus retinitis
IVTG alone | IVG + IVTG | Total | |
---|---|---|---|
Patient-specific characteristics | N = 23 | N = 26 | N = 49 |
Age in years (mean ± SD) | 40.52 ± 11.62 | 38.62 ± 7.01 | 39.51 ± 9.40 |
Male (%) | 12 (52.17) | 16 (61.54) | 28 (57.14) |
Bilateral involvement (%) | 4 (17.39) | 14 (53.85) | 18 (36.73) |
HIV infection (%) | 20 (86.96) | 26 (100) | 46 (93.88) |
Concurrent anti-retroviral therapy (%) | 13 (56.52) | 21 (80.77) | 34 (69.39) |
Mean initial CD4 (cells/mm3)(range) | 49.50 (1–482) | 45.60 (2–200) | 47.23 (1–482) |
Eye-specific characteristics | N = 27 | N = 40 | N = 67 |
Initial visual acuity (%) | |||
-6/60 or better | 19 (70.37) | 28 (70.00) | 47 (70.15) |
-worse than 6/60 to HM | 6 (22.22) | 10 (25.00) | 16 (23.88) |
-worse than HM | 2 (7.41) | 2 (5.00) | 4 (5.97) |
Initial IOP in mmHg (mean ± SD) | 12.00 ± 5.90 | 10.58 ± 2.81 | 11.15 ± 4.34 |
Initial anterior chamber cella (%) | |||
-2+ or less | 23 (85.19) | 33 (82.50) | 56 (83.58) |
-more than 2+ | 4 (14.81) | 7 (17.50) | 11 (16.42) |
Initial vitreous cella (%) | |||
-2+ or less | 25 (92.59) | 37 (92.50) | 62 (92.54) |
-more than 2+ | 2 (7.41) | 3 (7.50) | 5 (7.46) |
Worst location involvedb (%) | |||
-Zone 1 | 12 (44.45) | 21 (52.50) | 33 (49.25) |
-Zone 2 | 14 (51.85) | 16 (40.00) | 30 (44.78) |
-Zone 3 | 1 (3.70) | 3 (7.50) | 4 (5.97) |
Location size (%) | |||
-less than 25 % | 6 (22.22) | 5 (12.50) | 11 (16.42) |
-25–49 % | 18 (66.67) | 31 (72.50) | 49 (73.13) |
-50 % and more | 3 (11.11) | 4 (10.00) | 7 (10.45) |
Frosted branch angiitis presented (%) | 17 (62.96) | 30 (75.00) | 47 (70.15) |
Papillitis presented (%) | 8 (29.63) | 6 (15.00) | 14 (20.89) |
Foveal involvement (%) | 9 (33.33) | 13 (32.50) | 22 (32.84) |