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Table 1 Baseline characteristics of patients with cytomegalovirus retinitis

From: Treatment outcomes of reduced-dose intravitreal ganciclovir for cytomegalovirus retinitis

  IVTG alone IVG + IVTG Total
Patient-specific characteristics N = 23 N = 26 N = 49
Age in years (mean ± SD) 40.52 ± 11.62 38.62 ± 7.01 39.51 ± 9.40
Male (%) 12 (52.17) 16 (61.54) 28 (57.14)
Bilateral involvement (%) 4 (17.39) 14 (53.85) 18 (36.73)
HIV infection (%) 20 (86.96) 26 (100) 46 (93.88)
Concurrent anti-retroviral therapy (%) 13 (56.52) 21 (80.77) 34 (69.39)
Mean initial CD4 (cells/mm3)(range) 49.50 (1–482) 45.60 (2–200) 47.23 (1–482)
Eye-specific characteristics N = 27 N = 40 N = 67
Initial visual acuity (%)
 -6/60 or better 19 (70.37) 28 (70.00) 47 (70.15)
 -worse than 6/60 to HM 6 (22.22) 10 (25.00) 16 (23.88)
 -worse than HM 2 (7.41) 2 (5.00) 4 (5.97)
Initial IOP in mmHg (mean ± SD) 12.00 ± 5.90 10.58 ± 2.81 11.15 ± 4.34
Initial anterior chamber cella (%)
 -2+ or less 23 (85.19) 33 (82.50) 56 (83.58)
 -more than 2+ 4 (14.81) 7 (17.50) 11 (16.42)
Initial vitreous cella (%)
 -2+ or less 25 (92.59) 37 (92.50) 62 (92.54)
 -more than 2+ 2 (7.41) 3 (7.50) 5 (7.46)
Worst location involvedb (%)
 -Zone 1 12 (44.45) 21 (52.50) 33 (49.25)
 -Zone 2 14 (51.85) 16 (40.00) 30 (44.78)
 -Zone 3 1 (3.70) 3 (7.50) 4 (5.97)
Location size (%)
 -less than 25 % 6 (22.22) 5 (12.50) 11 (16.42)
 -25–49 % 18 (66.67) 31 (72.50) 49 (73.13)
 -50 % and more 3 (11.11) 4 (10.00) 7 (10.45)
Frosted branch angiitis presented (%) 17 (62.96) 30 (75.00) 47 (70.15)
Papillitis presented (%) 8 (29.63) 6 (15.00) 14 (20.89)
Foveal involvement (%) 9 (33.33) 13 (32.50) 22 (32.84)
  1. IVTG intravitreal ganciclovir, IVG intravenous ganciclovir, IOP intraocular pressure, HM hand motion, SD standard deviation
  2. aAnterior and vitreous reaction according to the Standardization of Uveitis Nomenclature guideline
  3. bWorst zone of retina involved; Zone 1, lesions located in the area of the retina within 1500 microns from the edge of the optic nerve or within 3000 microns from the centre of the fovea. Zone 2, lesion located from the edge of zone 1 anteriorly to the circle of the vortex vein. Zone 3, lesion located anteriorly from zone 2 to the ora serrata