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Table 1 Mean counts (Log10 CFU/ml) after 10-day exposure to Isoniazid and Rifampicin

From: Mycobacterium tuberculosis Uganda II is more susceptible to rifampicin and isoniazid compared to Beijing and Delhi/CAS families

Strain/

genotype

Isoniazid

Rifampicin

Aerobic

Oxygen depleted

Aerobic

Oxygen depleted

1x MIC

2x MIC

5x MIC

1x MIC

2x MIC

5x MIC

1x MIC

2x MIC

5x MIC

1x MIC

2x MIC

5x MIC

Uganda II

5.29

4.06

3.12

7.51

7.56

7.22*

5.45

4.11

2.86

5.03

3.91*

3.03*

Delhi/CAS

6.10

4.47

3.23

7.64

7.67

7.49

5.27

2.96

2.96

7.43

6.58*

5.23*

Beijing

5.48

4.10

3.30

7.64

7.51

7.36*

5.44

2.93

2.93

7.39

6.53

5.14*

  1. *Where P-value was <0.05 when compared to Uganda II