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Table 1 Mean counts (Log10 CFU/ml) after 10-day exposure to Isoniazid and Rifampicin

From: Mycobacterium tuberculosis Uganda II is more susceptible to rifampicin and isoniazid compared to Beijing and Delhi/CAS families

Strain/
genotype
Isoniazid Rifampicin
Aerobic Oxygen depleted Aerobic Oxygen depleted
1x MIC 2x MIC 5x MIC 1x MIC 2x MIC 5x MIC 1x MIC 2x MIC 5x MIC 1x MIC 2x MIC 5x MIC
Uganda II 5.29 4.06 3.12 7.51 7.56 7.22* 5.45 4.11 2.86 5.03 3.91* 3.03*
Delhi/CAS 6.10 4.47 3.23 7.64 7.67 7.49 5.27 2.96 2.96 7.43 6.58* 5.23*
Beijing 5.48 4.10 3.30 7.64 7.51 7.36* 5.44 2.93 2.93 7.39 6.53 5.14*
  1. *Where P-value was <0.05 when compared to Uganda II