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Table 1 MICs of various antifungal agents against 11 clinical Trichosporon dermatis isolates

From: Emerging pan-resistance in Trichosporon species: a case report

T. dermatis strains tested MIC (mg/liter) Method Reference
  Amphotericin Ba Flucytosine Fluconazole Itraconazole Voriconazole Posaconazole Caspofungin   
  GM Range GM Range GM Range GM Range GM Range GM Range GM Range   
1 0.25   >64   >256   >16   >16   >8   >16   Sensititreb Our study
8 0.24 0.015-16.0 58.6 16.0-128.0 12.3 1.0-128.0 0.58 0.06-8.0 0.48 0.06-16.0 ND   ND   Eucast Rodriguez-Tudela et al 2005 [7]
1 0.5   8     0.06   0.06   ND   16   CLSI Chagas-Neto et al 2009 [2]
1 0.13   ND   2   0.06   0.06   0.015   ND   Eucast Taverna et al. 2014 [16]
  1. GM geometrical mean, MIC minimal inhibitory concentration, ND not done
  2. aEffectiveness of amphotericin B is limited in Trichosporon infections [12]
  3. bSusceptibility was tested using a commercial microdilution test (Yeast Sensititre OneTM) by the national reference center (Radboud University Medical Center, Nijmegen, The Netherlands)