Fig. 2From: Naïve-pooled pharmacokinetic analysis of pyrazinamide, isoniazid and rifampicin in plasma and cerebrospinal fluid of Vietnamese children with tuberculous meningitisPlasma (open circles) and CSF (grey squares) concentration-time profiles for isoniazid stratified for age (<4 years old [left] and > 4 years old [right]). Continuous lines represent the median plasma concentration and broken lines represent the plasma upper and lower quartiles. Black stars represent plasma samples with concentrations below LOQ. Sub-therapeutic threshold: 3 μg/mL; Minimum Inhibitory Concentration (MIC) and Limit of Quantification (LOQ): 0.2 μg/mLBack to article page