Negative attitude and low intention to vaccinate universally against varicella among public health professionals and parents in the Netherlands: two internet surveys

van Lier, Alies; Tostmann, Alma; Harmsen, Irene A.; de Melker, Hester E.; Hautvast, Jeannine L. A.; Ruijs, Wilhelmina L. M.

doi:10.1186/s12879-016-1442-1

Table 5 Determinants for a positive attitude (professionals) or positive intention (parents) regarding universal varicella vaccination from univariable and multivariable logistic regression analysis

From: Negative attitude and low intention to vaccinate universally against varicella among public health professionals and parents in the Netherlands: two internet surveys

	Professionals (RPHS & CHC combined)				Parents
Potential determinants	N	Outcome^a: positive attitude % [95 % CI]	Crude OR [95 % CI]	Adjusted OR [95 % CI]	N	Outcome^a: positive intention % [95 % CI]	Crude OR [95 % CI]	Adjusted OR [95 % CI]
Sex
Male	40	22.5 [12.3–37.5]	Reference	Reference	90	27.8 [19.6–37.8]	Reference	Reference
Female	364	20.6 [16.8–25.1]	0.9 [0.4–2.0]	1.7 [0.6–4.6]	401	28.2 [24.0–32.8]	1.0 [0.6–1.7]	1.0 [0.5–2.0]
Age
Younger than 30 years	38	28.9 [17.0–44.8]	Reference	Reference	94	23.4 [16.0–32.9]	Reference	Reference
30–34 years	48	29.2 [18.2–43.2]	1.0 [0.4–2.6]	0.7 [0.2–2.2]	189	35.4 [29.0–42.5]	1.8 [1.0–3.2]^b	1.8 [0.8–3.8]
35–39 years	40	25.0 [14.2–40.2]	0.8 [0.3–2.2]	0.8 [0.2–2.9]	148	20.3 [14.6–27.5]	0.8 [0.4–1.6]	1.1 [0.5–2.6]
40 years or older	278	17.6 [13.6–22.5]	0.5 [0.2–1.1]	0.4 [0.1–1.0]	60	31.7 [21.3–44.2]	1.5 [0.7–3.1]	1.2 [0.4–3.4]
Profession
Medical doctor	151	27.8 [21.3–35.4]	Reference	Reference	-
Nurse	253	16.6 [12.5–21.7]	0.5 [0.3–0.8]^b	1.0 [0.5–1.9]	-
Education level
High					274	27.0 [22.1–32.6]	Reference	Reference
Medium					166	27.1 [20.9–34.3]	1.0 [0.7–1.6]	0.9 [0.5–1.7]
Low					51	37.3 [25.3–51.0]	1.6 [0.9–3.0]	1.0 [0.4–2.4]
Knowledge about VZV (max. 5 points)
Limited knowledge (0–2 points)	56	17.9 [10.0–29.8]	Reference	Reference	177	35.0 [28.4–42.3]	Reference	Reference
Moderate knowledge (3 points)	113	18.6 [12.5–26.7]	1.1 [0.5–2.4]	1.0 [0.4–2.9]	209	23.0 [17.8–29.1]	0.6 [0.4–0.9]^b	0.9 [0.5–1.6]
Good knowledge (4–5 points)	235	22.6 [17.7–28.3]	1.3 [0.6–2.8]	1.1 [0.4–2.8]	105	26.7 [19.1–35.8]	0.7 [0.4–1.1]	1.4 [0.7–3.0]
Beliefs about the disease varicella and varicella vaccination
Varicella generally has a mild disease course in healthy children
No agreement	12	58.3 [32.0–80.7]	Reference	Reference	22	54.5 [34.7–73.1]	Reference	Reference
Neutral	24	29.2 [14.9–49.2]	0.3 [0.1–1.3]	0.2 [0.03–1.3]	76	51.3 [40.3–62.2]	0.9 [0.3–2.3]	0.7 [0.2–2.5]
Agreement	368	19.0 [15.3–23.3]	0.2 [0.1–0.5]^b	0.2 [0.04–0.9]^b	393	22.1 [18.3–26.5]	0.2 [0.1–0.6]^b	0.5 [0.1–1.4]
Varicella can cause serious complications
No agreement	42	16.7 [8.3–30.6]	Reference	Reference	66	12.1 [6.3–22.1]	Reference	Reference
Neutral	98	8.2 [4.2–15.3]	0.4 [0.2–1.3]	0.6 [0.2–2.4]	218	20.2 [15.4–26.0]	1.8 [0.8–4.1]	1.0 [0.4–2.7]
Agreement	264	26.1 [21.2–31.8]	1.8 [0.8–4.2]	1.5 [0.5–4.8]	207	41.5 [35.0–48.4]	5.2 [2.3–11.3]^b	1.3 [0.4–3.5]
Varicella is a disease one could better have been through
No agreement	22	59.1 [38.7–76.7]	Reference	Reference	46	60.9 [46.5–73.6]	Reference	Reference
Neutral	73	23.3 [15.1–34.2]	0.2 [0.1–0.6]^b	0.3 [0.1–1.3]	126	41.3 [33.1–50.0]	0.5 [0.2–0.9]^b	0.5 [0.2–1.3]
Agreement	309	17.5 [13.6–22.1]	0.1 [0.1–0.4]^b	0.3 [0.1–1.0]	319	18.2 [14.3–22.8]	0.1 [0.1–0.3]^b	0.4 [0.1–0.9]^b
I am worried about the side effects of varicella vaccination
No agreement	163	30.1 [23.5–37.5]	Reference	Reference	115	27.0 [19.7–35.7]	Reference	Reference
Neutral	190	15.3 [10.8–21.1]	0.4 [0.3–0.7]^b	0.6 [0.3–1.1]	196	29.1 [23.2–35.8]	1.1 [0.7–1.9]	0.5 [0.2–1.1]
Agreement	51	11.8 [5.5–23.4]	0.3 [0.1–0.8]^b	0.5 [0.1–1.4]	180	27.8 [21.8–34.7]	1.0 [0.6–1.8]	0.7 [0.3–1.5]
I think varicella is a disease serious enough to vaccinate against
No agreement	255	9.8 [6.7–14.1]	Reference	Reference	289	8.3 [5.6–12.1]	Reference	Reference
Neutral	107	28.0 [20.4–37.2]	3.6 [2.0–6.5]^b	2.4 [1.2–4.7]^b	102	32.4 [24.1–41.9]	5.3 [2.9–9.5]^b	4.9 [2.3–10.6]^b
Agreement	42	69.0 [54.0–80.9]	20.5 [9.5–44.5]^b	9.9 [3.9–24.9]^b	100	81.0 [72.2–87.5]	47.1 [24.5–90.3]^b	26.2 [10.8–63.4]^b
I think most parents will vaccinate their child against varicella
No agreement	225	9.8 [6.5–14.4]	Reference	Reference	182	9.9 [6.3–15.1]	Reference	Reference
Neutral	96	26.0 [18.3–35.6]	3.2 [1.7–6.1]^b	2.3 [1.1–4.9]^b	184	24.5 [18.8–31.1]	3.0 [1.6–5.3]^b	1.1 [0.5–2.4]
Agreement	83	44.6 [34.4–55.3]	7.4 [4.0–13.8]^b	4.2 [2.0–8.6]^b	125	60.0 [51.2–68.2]	13.7 [7.5–25.0]^b	2.0 [0.8–4.6]
Total	404	20.8 [17.1–25.0]			491	28.1 [24.3–32.2]

RPHS = regional public health service; CHC = child health clinic; OR = odds ratio; CI = confidence interval
^aOutcome professionals: attitude towards universal childhood varicella vaccination (1 = positive (all children) or 0 = neutral or negative (nobody or high-risk groups only) attitude); outcome parents: intention regarding vaccination own child against varicella within the National Immunisation Programme (free of charge; 1 = positive or 0 = neutral or negative intention)
^bStatistically significant (p < 0.05) association with the outcome

Back to article page

ISSN: 1471-2334

Contact us

Submission enquiries: bmcinfectiousdiseases@biomedcentral.com
General enquiries: ORSupport@springernature.com

BMC Infectious Diseases

Contact us