Early detection of novel Leishmania species DNA in the saliva of two HIV-infected patients

BMC Infectious Diseases

Table 1 Clinical presentations, CD4+ T cell levels, PCR, and Culture/Tissue biopsy for Leishmania parasite^a

Patient	Clinical Presentation	CD4+ T cell count (cells/mm³)	Results of PCR for Leishmania									Culture/Tissue biopsy for Leishmania
			First sample collection			Second sample collection			Third sample collection			Culture/Tissue biopsy for Leishmania
			S	B	BF	S	B	BF	S	B	BF
32 year old	Relapse disseminated CL 2 years after treatment	110	+	+	+	Not collected			Not collected			+/+
Male	Relapse disseminated CL 2 years after treatment	110	+	+	+	Not collected			Not collected			+/+
48 year old	Nodular CL, relapse 2 years after treatment for disseminated CL	207	+	-	-	+	-	-	+	-	+	+/+
Male		207	+	-	-	+	-	-	+	-	+	+/+
28 year old	Asymptomatic	617	+	-	-	+	-	-	+	-	-	-/N/A
Female	Asymptomatic	617	+	-	-	+	-	-	+	-	-	-/N/A

^a S Saliva; B Blood; BF Buffy coat; +: positive; −: Negative; N/A: not available; CL: Cutaneous leishmaniasis

ISSN: 1471-2334