Table 2 Outcomes of singleton pregnancies with LPV/r exposure (n=4762)

Total live births, n (%)

4556 (95.7)

ᅟConception on LPV/r, n

863

ᅟInitiation of LPV/r, n

3693

Mode of delivery, n (%)

n=4541

ᅟVaginal delivery

1664 (36.6)

ᅟElective caesarean delivery

1776 (39.1)

ᅟEmergency caesarean delivery

1101 (24.3)

Gestational age

n=4556

ᅟMedian (IQR), wk

38 (38–39)

ᅟ<32 wk, n (%)

112 (2.5)

ᅟ32–36 wk, n (%)

473 (10.4)

ᅟ≥37 wk, n (%)

3971 (87.2)

Birth weight

n=4395

ᅟMedian (IQR), g

3030 (2710–3360)

ᅟ<1500 g, n (%)

101 (2.3)

ᅟ1500–2499 g, n (%)

545 (12.4)

ᅟ≥2500 g, n (%)

3749 (85.3)

Infant mortality, n

24

ᅟᅟ<32 wk, n/N, per 1000 infants (95 % CI)

14/112, 125.0 per 1000 infants (62.8–187.2)

ᅟᅟ32–36 wk, n/N, per 1000 infants (95 % CI)

4/473, 8.5 per 1000 infants (0.2–16.7)

ᅟᅟTerm, n/N, per 1000 infants (95 % CI)

6/3971, 1.5 per 1000 infants (0.3–2.7)

Stillbirth, n (%)

44 (0.9)

ᅟConception on LPV/r, n/N (%)

7/952 (0.7)

ᅟInitiation of LPV/r, n/N (%)

37/3810 (1.0)

ᅟᅟ<32 wk, n/N, per 1000 infants (95 % CI)

23/135, 170.4 per 1000 infants (106.1–234.6)

ᅟᅟ32–36 wk, n/N, per 1000 infants (95 % CI)

8/481, 16.6 per 1000 infants (5.2–28.1)

ᅟᅟTerm, n/N, per 1000 infants (95 % CI)

13/3984, 3.3 per 1000 infants (1.5–5.0)

Miscarriage or termination,^a n (%)

120 (2.5)

ᅟConception on LPV/r, n/N (%)

76/952 (8.0)

ᅟInitiation of LPV/r, n/N (%)

44/3810 (1.2)

Left United Kingdom/Ireland before delivery, n (%)

42 (0.9)