Table 1 Univariate logistic analyses, variables associated with all-cause 30-day in-hospital mortality

Demography

Age, years, mean ± SD

65.7 ± 15.5

74.6 ± 9.5

1.05, 1.0–1.10

0.08

Male sex^b

42 (70.0)

8 (72.7)

0.88, 0.21–3.68

0.86

Predisposing conditions

None^c

7 (11.7)

0

-

1.00

Myocardial infarction^c,d

21 (35.0)

5 (45.5)

1.55, 0.42–5.68

0.51

Congestive heart failure^c,d

8 (13.3)

4 (36.4)

3.71, 0.88–15.62

0.07

Chronic pulmonary disease^c,d

13 (21.7)

2 (18.2)

0.08, 0.15–4.19

0.80

Diabetes^c,d

17 (28.3)

2 (18.2)

0.56, 0.11–2.87

0.49

Leukemia^c,d

4 (6.7)

4 (36.4)

8.0, 1.63–39.35

0.01

Lymphoma^c,d

3 (5)

2 (18.2)

4.22, 0.62–28.87

0.14

Solid tumor^c,d

6 (10)

0

-

0.58

Metastatic cancer^c,d

2 (3.3)

1 (9.1)

2.9, 0.24–35.07

0.40

Steroid treatment^{c, e}

7 (11.7)

3 (27.3)

2.84, 0.61–13.30

0.19

Chemotherapy^{c, e}

7 (11.7)

3 (27.3)

2.84, 0.61–13.30

0.19

Current smoker^c

23 (38.3)

2 (18.2)

0.36, 0.07–1.80

0.21

Ever smoked^c

35 (58.3)

6 (54.5)

0.86, 0.24–3.12

0.82

Hospitalization within 30 days^c

6 (10)

4 (36.4)

5.14, 1.16–22.82

0.03

Charlson comorbidity index, mean ± SD

2.3 ± 2.1

3.7 ± 2.1

1.33, 1.00–1.77

0.05

Laboratory variables at admission

Oxygen saturation, %, mean ±SD

92.1 ± 5.2

88.3 ± 10.7

0.92, 0.83–1.02

0.12

Neutrophil count < 1.0 x10⁹/L^c

2 (18.2)^g

7 (10.0)

2.4, 0.40–14.31

0.34

Lymphocyte count < 1.0 x10⁹/L^c

38 (64.4)^g

5 (45.5)

0.46, 0.13–1.69

0.24

Creatinine level, μmol/L, mean ± SD

123.8 ± 70.7

168.0 ± 106.1

1.60, 0.88–2.89

0.12

Bilateral infiltrates on chest X-ray^c

14 (23.3)

4 (36.4)

1.88, 0.48–7.36

0.37

Primary diagnosis by positive UAT^f

14 (23.3)

7 (63.6)

0.17, 0.04–0.68

0.01

Antibiotic therapy & outcome

Appropriate therapy on day +1^c

37 (61.7)

3 (27.3)

0.23, 0.06–0.98

0.05

Appropriate therapy on day +2 ^c

52 (86.7)

4 (36.4)

0.09, 0.02–0.37

0.001

Delay in appropriate therapy administration, days, mean ± SD

0.9 ± 1.8

4.2 ± 5.6

1.34, 1.08–1.67

0.01

Quinolones started on day +1^c

17 (28.3)

3 (27.3)

1.13, 0.26–4.80

0.87

Quinolones started on day +2^c

23 (38.3)

4 (36.4)

0.92, 0.24–3.49

0.90

ICU admission^c

12 (20.0)

9 (81.8)

18.00, 3.43–94.44

0.001

Invasive ventilation ^c

10 (16.7)

8 (72.7)

13.33, 3.00–59.19

0.001