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Table 1 Demographics and Baseline Characteristics of Study Subjects

From: A phase 1 randomized, double-blind, placebo-controlled, crossover trial of DAS181 (Fludase®) in adult subjects with well-controlled asthma

Characteristic

Evaluable subjects

N = 10

Age (years)

 

 Median (IQR)

22.5 (22, 40)

Sex

 

 Female

7 (70 %)

 Male

3 (30 %)

Race

 

 White

5 (50 %)

 Black or African American

3 (30 %)

 Asian

1 (10 %)

 Multi-Racial

1 (10 %)

Body Mass Index (kg/m2)

 

 Median (IQR)

23.0 (21.4, 24.3)

FEV1, Baseline (day 0)

 

Median (IQR)

3.09 (2.78, 3.62)

FEV1 % Predicted, Baseline (day 0)

 

Mean (SD)

95.1 (11.6)

PC20, Baseline (screening, mg/m2)

 

 Median (IQR)

1.79 (0.49, 3.62)

Asthma Medications (baseline)

 

 Short Acting Beta Agonist, inhaled

9 (90 %)

 Long Acting Beta Agonist/Glucocorticoid, inhaled

2 (20 %)

 Glucocorticoid, inhaled

1 (10 %)

 Leukotriene-receptor antagonist

2 (20 %)

  1. Abbreviations: IQR interquartile range, FEV1 forced expiratory volume in 1 second, SD standard deviation, PC 20 provocative concentration producing a 20 % decline (PC20)