n | Cases (n = 44) | n | Controls (n = 371) | p | |
---|---|---|---|---|---|
Change in FEV1, %, mean (SD) | |||||
Month 1 | 12 | 8.3 (19.2) | 198 | −2.3 (8.4) | 0.08 |
Month 3 | 17 | 0.6 (7.8) | 211 | −2.5 (8.7) | 0.14 |
Month 12 | 28 | 1.2 (13.3) | 249 | −1.8 (11.0) | 0.67 |
Change in FVC, %, mean (SD) | |||||
Month 1 | 12 | 7.4 (18.1) | 198 | −3.9 (8.8) | 0.05 |
Month 3 | 17 | 0.7 (8.7) | 212 | −2.5 (8.9) | 0.16 |
Month 12 | 28 | 1.9 (12.7) | 252 | −2.6 (9.8) | 0.10 |
Antibiotics, number of treatments, mean (SD) | |||||
Oral | 44 | 2.8 (2.4) | 371 | 1.8 (2.1) | 0.002 |
Intravenous | 44 | 0.6 (1.3) | 371 | 0.8 (1.54) | 0.42 |
New bronchopulmonary colonization, n (%) | |||||
Any germ | 44 | 13 (30) | 371 | 151 (41) | 0.60 |
H. influenza | 44 | 1 (2) | 371 | 32 (8) | 0.13 |
S. aureus | 44 | 3 (7) | 371 | 39 (11) | 0.42 |
P. aeruginosa | 44 | 6 (14) | 371 | 36 (10) | 0.48 |
B. cepacia | 44 | 0 | 371 | 5 (1) | 0.42 |
A. fumigatus | 44 | 3 (7) | 371 | 39 (11) | 0.42 |
Oxygen therapy, n (%) | 44 | 2 (5) | 371 | 30 (8) | 0.41 |
Noninvasive ventilation, n (%) | 44 | 2 (5) | 371 | 12 (3) | 0.65 |