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Table 2 Characteristics of cases and controls during the year after A/H1N1 2009 pandemic influenza

From: Lessons from a French collaborative case–control study in cystic fibrosis patients during the 2009 A/H1N1 influenza pandemy

 

n

Cases (n = 44)

n

Controls (n = 371)

p

Change in FEV1, %, mean (SD)

    

 Month 1

12

8.3 (19.2)

198

−2.3 (8.4)

0.08

 Month 3

17

0.6 (7.8)

211

−2.5 (8.7)

0.14

 Month 12

28

1.2 (13.3)

249

−1.8 (11.0)

0.67

Change in FVC, %, mean (SD)

    

 Month 1

12

7.4 (18.1)

198

−3.9 (8.8)

0.05

 Month 3

17

0.7 (8.7)

212

−2.5 (8.9)

0.16

 Month 12

28

1.9 (12.7)

252

−2.6 (9.8)

0.10

Antibiotics, number of treatments, mean (SD)

   

 Oral

44

2.8 (2.4)

371

1.8 (2.1)

0.002

 Intravenous

44

0.6 (1.3)

371

0.8 (1.54)

0.42

New bronchopulmonary colonization, n (%)

   

 Any germ

44

13 (30)

371

151 (41)

0.60

H. influenza

44

1 (2)

371

32 (8)

0.13

S. aureus

44

3 (7)

371

39 (11)

0.42

P. aeruginosa

44

6 (14)

371

36 (10)

0.48

B. cepacia

44

0

371

5 (1)

0.42

A. fumigatus

44

3 (7)

371

39 (11)

0.42

Oxygen therapy, n (%)

44

2 (5)

371

30 (8)

0.41

Noninvasive ventilation, n (%)

44

2 (5)

371

12 (3)

0.65

  1. Both are compared to reference data and expressed as percent predicted values, based on age, gender, and height
  2. FEV1 forced expiratory volume in one second, FVC forced vital capacity, SD standard deviation