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Table 1 Sporotrichosis clinical presentation, diagnosis and treatment

From: Epidemiological investigation of an outbreak of cutaneous sporotrichosis, Northern Territory, Australia

Case

Other medical problems

Month of symptom onset

Time to diagnosis (months)a

Site of primary lesion

Sporotrichoid spread

Multiple lesions

Culture confirmed

Sequence type (ST); Genbank accession

Itraconazole dose prescribed

Treatment duration (months)

1

Hypertension

May

2

Lower leg (R)

Yes

Yes

Yes

ST 1; KU041841

200 mg daily

3

2

N/A

May

2

Multiple (both arms, chest, left leg)

No

Yes

Yes

ST 2;

KU097326

200 mg daily

4

3

N/A

May

2

Forearm (R)

Yes

Yes

Yes

ST 1;

KU041840

200 mg daily

6

4

N/A

May

2

Finger (R)

Yes

Yes

Nob

N/A

100 mg daily

3

5

Smoker

July

1

Hand (R)

Yes

Yes

Yes

ST 2; KU041843

200 mg daily

3

6

Ischaemic heart disease, hazardous alcohol

May

3

Lower leg (R)

No

No

Yes

ST 2; KU041846

200 mg daily

3

7

N/A

April

4

Cubital fossa (R)

Yes

Yes

Yesc

N/A

200 mg daily

6

8

Hypertension

April

5

Thigh (R)

No

Yes

Yes

ST 2; KU041845

200 mg daily

4

9

N/A

April

11

Forearm (L)

Yes

Yes

Yes

ST 1;

KU041842

200 mg daily

Ongoing

  1. aTime from onset of symptoms to confirmation of diagnosis (by culture or histopathology)
  2. bFungal culture not performed. Diagnosis based on characteristic histopathology findings and consistent clinical and epidemiological features
  3. cIsolate could not be revived for ITS sequencing following its morphological identification as S. schenckii complex