Table 3 Relationship between pneumococcal vaccination status and pneumococcal carriage in children with asthma
Vaccinated with PCV7 (n = 195) n (%) | Not vaccinated against pneumococcus (n = 228) n (%) | Crude OR (95 % CI) | OR (95 % CI)a | |
|---|---|---|---|---|
Pneumococcal carrier status | ||||
Any serotype | ||||
Non-carriers | 102 (44.2) | 129 (55.8) | 1 (reference) | 1 (reference) |
Carriers | 93 (48.4) | 99 (51.6) | 1.19 (0.81–1.74) | 1.05 (0.70–1.58) |
Serotypes in PCV7 | ||||
Non-carriers | 107 (43.8) | 137 (56.2) | 1 (reference) | 1 (reference) |
Carriers | 88 (49.2) | 91 (50.8) | 1.24 (0.84–1.82) | 1.08 (0.72–1.62) |
Six additional serotypes in PCV13 | ||||
Non-carriers | 162 (46.7) | 185 (53.3) | 1 (reference) | 1 (reference) |
Carriers | 33 (43.4) | 43 (56.6) | 0.88 (0.53–1.45) | 0.76 (0.45–1.28) |
Subgroup aged <10 years | (n = 95) | (n = 81) | ||
Any serotype | ||||
Non-carriers | 45 (54.2) | 38 (45.8) | 1 (reference) | 1 (reference) |
Carriers | 50 (53.8) | 43 (46.2) | 0.98 (0.54–1.78) | 1.01 (0.55–1.86) |
Serotypes in PCV7 | ||||
Non-carriers | 49 (55.1) | 40 (44.9) | 1 (reference) | 1 (reference) |
Carriers | 46 (52.9) | 41 (47.1) | 0.92 (0.51–1.66) | 0.93 (0.51–1.72) |
Six additional serotypes in PCV13 | ||||
Non-carriers | 74 (54.4) | 62 (45.6) | 1 (reference) | 1 (reference) |
Carriers | 21 (52.5) | 19 (47.5) | 0.93 (0.46–1.88) | 0.98 (0.47–2.03) |
Subgroup aged 10–14 years | (n = 87) | (n = 120) | ||
Any serotype | ||||
Non-carriers | 47 (40.2) | 70 (59.8) | 1 (reference) | 1 (reference) |
Carriers | 40 (44.4) | 50 (55.6) | 1.19 (0.68–2.08) | 1.08 (0.61–1.94) |
Serotypes in PCV7 | ||||
Non-carriers | 47 (38.8) | 74 (61.2) | 1 (reference) | 1 (reference) |
Carriers | 40 (46.5) | 46 (53.5) | 1.37 (0.78–2.40) | 1.22 (0.68–2.20) |
Six additional serotypes in PCV13 | ||||
Non-carriers | 76 (43.7) | 98 (56.3) | 1 (reference) | 1 (reference) |
Carriers | 11 (33.3) | 22 (66.7) | 0.65 (0.29–1.41) | 0.54 (0.23–1.26) |