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Table 4 Drug susceptibilities profile and genetic mutation of the major clonal complexes in Mtb strains isolated from single infection patients

From: Drug resistance characteristics and cluster analysis of M. tuberculosis in Chinese patients with multiple episodes of anti-tuberculosis treatment

  Total. MDR only MDR-FQR MDR-INJR XDR katG rpoB pncA gyrA rrs eis
Clone 1 67 31 (46.3) 5 (7.5) 4 (6.0) 2 (3.0) 37 (55.2) 39 (58.2) 21 (31.3) 5 (7.5) 4 (6.0) 3 (4.5)
Clone 2 2 0 (0.0) 0 (0.0) 1 (50.0) 0 (0.0) 1 (50.0) 1 (50.0) 1 (50.0) 1 (50.0) 1 (50.0) 0 (0.0)
Clone 3 2 1 (50.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (50.0) 1 (50.0) 1 (50.0) 0 (0.0) 0 (0.0) 0 (0.0)
Clone 4 2 2 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 2 (100.0) 2 (100.0) 1 (50.0) 0 (0.0) 0 (0.0) 0 (0.0)
Clone 5 2 1 (50.0) 2 (100.0) 0 (0.0) 0 (0.0) 1 (50.0) 1 (50.0) 0 (0.0) 2 (100.0) 0 (0.0) 0 (0.0)
Clone 6 4 3 (75.0) 1 (25.0) 0 (0.0) 0 (0.0) 4 (100.0) 2 (50.0) 1 (25.0) 0 (0) 1 (25.0) 0 (0.0)
Clone 7 2 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (50.0) 0 (0.0) 0 (0.0)
Clone 8 2 1 (50.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (50.0) 0 (0.0) 1 (50.0) 0 (0) 0 (0.0) 0 (0.0)
Clone 9 2 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (50.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 1 (50.0)
Clone 10 2 2 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 2 (100.0) 0 (0.0) 0 (0) 0 (0.0) 0 (0.0)
Clone 11 3 1 (33.3) 1 (33.3) 0 (0.0) 0 (0.0) 3 (100) 1 (33.3) 1 (33.3) 0 (0) 0 (0.0) 0 (0.0)
Singleton 44 11 (25.0)* 0 (0.0)* 1 (2.3) 0 (0.0)* 8 (18.2)* 7 (15.9)* 12 (27.3) 2 (4.5)* 1 (2.3) 0 (0.0)
  1. MDR multidrug resistance, XDR extensively drug resistance, FQR fluoroquinolones resistance, INJR injective drug resistance
  2. *p < 0.05 in comparison to the clone group