Table 4 Drug susceptibilities profile and genetic mutation of the major clonal complexes in Mtb strains isolated from single infection patients
Total. | MDR only | MDR-FQR | MDR-INJR | XDR | katG | rpoB | pncA | gyrA | rrs | eis | |
|---|---|---|---|---|---|---|---|---|---|---|---|
Clone 1 | 67 | 31 (46.3) | 5 (7.5) | 4 (6.0) | 2 (3.0) | 37 (55.2) | 39 (58.2) | 21 (31.3) | 5 (7.5) | 4 (6.0) | 3 (4.5) |
Clone 2 | 2 | 0 (0.0) | 0 (0.0) | 1 (50.0) | 0 (0.0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 0 (0.0) |
Clone 3 | 2 | 1 (50.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Clone 4 | 2 | 2 (100.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (100.0) | 2 (100.0) | 1 (50.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Clone 5 | 2 | 1 (50.0) | 2 (100.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) | 1 (50.0) | 0 (0.0) | 2 (100.0) | 0 (0.0) | 0 (0.0) |
Clone 6 | 4 | 3 (75.0) | 1 (25.0) | 0 (0.0) | 0 (0.0) | 4 (100.0) | 2 (50.0) | 1 (25.0) | 0 (0) | 1 (25.0) | 0 (0.0) |
Clone 7 | 2 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) | 0 (0.0) | 0 (0.0) |
Clone 8 | 2 | 1 (50.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) | 0 (0.0) | 1 (50.0) | 0 (0) | 0 (0.0) | 0 (0.0) |
Clone 9 | 2 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) |
Clone 10 | 2 | 2 (100.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (100.0) | 0 (0.0) | 0 (0) | 0 (0.0) | 0 (0.0) |
Clone 11 | 3 | 1 (33.3) | 1 (33.3) | 0 (0.0) | 0 (0.0) | 3 (100) | 1 (33.3) | 1 (33.3) | 0 (0) | 0 (0.0) | 0 (0.0) |
Singleton | 44 | 11 (25.0)* | 0 (0.0)* | 1 (2.3) | 0 (0.0)* | 8 (18.2)* | 7 (15.9)* | 12 (27.3) | 2 (4.5)* | 1 (2.3) | 0 (0.0) |