From: Risk factors for infection following prostate biopsy - a case control study
 | Cases | Controls | OR (95 % CI) | P value |
---|---|---|---|---|
Number | 71 | 213 | Â | Â |
Patient variables | ||||
 Age > 65 years | 35 (49.3 %) | 92 (43.2 %) | 1.34 (0.74, 2.40) | 0.33 |
 Hospital employee | 5 (7.0 %) | 13 (6.1 %) | 1.16 (0.41, 3.33) | 0.78 |
 Autoimmune condition | 0 (0 %) | 10 (4.5 %) | Undefined | ND |
 Immunosuppression | 1 (1.4 %) | 3 (1.4 %) | 1.00 (0.08, 11.93) | 1.00 |
 COPD | 2 (2.8 %) | 4 (1.9 % | 1.50 (0.27, 8.19) | 0.64 |
 Heart valve replacement | 3 (4.2 %) | 3 (1.4 %) | 3.0 (0.61, 14.86) | 0.18 |
 Benign prostate enlargement | 14 (19.7 %) | 41 (19.2) | 1.24 (0.62, 2.43) | 0.54 |
 Diabetes | 10 (14.1 %) | 23 (10.8 %) | 1.35 (0.61, 2.96) | 0.46 |
 Recent travel | 13 (18.3 %) | 7 (3.2 %) | 5.40 (1.61, 18.09) | 0.01 |
 Recent antimicrobial use | 7 (9.8 %) | 3 (1.4 %) | 9.59 (1.97, 46.62) | 0.01 |
 Recent hospitalisation | 1 (1.4 %) | 0 (0.0 %) | Undefined | ND |
Procedural variables | ||||
 Use of FQ prophylaxis | 70 (98.6 %) | 213 (100.0 %) | Undefined | ND |
 Duration of FQ prophylaxis <7 days | 10 (14.1 %) | 44 (20.7 %) | 1.72 (0.71, 4.20) | 0.23 |
 Use of aminoglycoside prophylaxis | 19 (26.8 %) | 43 (20.2 %) | 1.85 (0.81, 4.24) | 0.14 |
 Use of a penicillin as prophylaxis | 19 (26.8 %) | 76 (35.7 %) | 0.42 (0.18, 0.98) | 0.05 |
 Use of carbapenem as prophylaxis | 0 | 21 (9.8 %) | Undefined | ND |
 Previous biopsy | 12 (16.9 %) | 36 (16.9 %) | 1.29 (0.62, 2.70) | 0.50 |
 Previous biopsy within 3 years | 11 (15.5 %) | 26 (12.2 %) | 1.31 (0.61, 2.83) | 0.48 |
 Urinary catheter | 0 (0 %) | 0 (0 %) | Undefined | ND |
 Preoperative urine culture | 1 (1.4 %) | 0 (0 %) | Undefined | ND |
 Use of enema | 31 (43.6 %) | 110 (51.6 %) | 0.71 (0.30, 1.69) | 0.44 |
 Prostate volume >30 mL | 53 (74.6 %) | 174 (81.7 %) | 1.38 (0.64, 2.93) | 0.41 |
 PSA > 4 mmol | 55 (77.4 %) | 168 (78.8 %) | Undefined | ND |
 Number of biopsy cores >12 | 46 (64.8 %) | 156 (73.2 %) | 0.37 (0.14, 0.95) | 0.04 |
 Prostate cancer | 42 (59.2 %) | 123 (57.7 %) | 1.15 (0.63, 2.07) | 0.65 |