The impact of HIV status and antiretroviral treatment on TB treatment outcomes of new tuberculosis patients attending co-located TB and ART services in South Africa: a retrospective cohort study

Table 2 Multinomial logistic regression of factors associated with treatment outcomes in new TB patients

	Defaulted vs. Success^a	Died vs. Success^a	Defaulted vs. Success^a	Died vs. Success^a
	Unadjusted OR (95 % CI)	Unadjusted OR (95 % CI)	Adjusted OR (95 % CI)^b	Adjusted OR (95 % CI)^b
Age, years	0.98 (0.96–1.00)	1.03** (1.01–1.05)	0.98* (0.96–1.00)	1.04** (1.02–1.07)
Gender
Male	Ref.	Ref.	Ref.	Ref.
Female	0.60* (0.38–0.94)	1.16 (0.62–2.19)	0.57* (0.35–0.91)	1.06 (0.55–2.06)
Type of TB
EPTB	Ref.	Ref.	Ref.	Ref.
Smear-negative PTB	0.98 (0.54–1.77)	0.81 (0.36–1.79)	0.88 (0.48–1.62)	0.60 (0.26–1.39)
Smear-positive PTB	0.85 (0.49–1.49)	0.61 (0.29–1.32)	0.69 (0.38–1.26)	0.59 (0.26–1.34)
HIV status
HIV-negative	Ref.	Ref.	Ref.	Ref.
HIV-positive on ART	0.70 (0.41–1.16)	0.72 (0.32–1.61)	0.71 (0.41–1.23)	0.80 (0.33–1.95)
HIV- positive not on ART	1.57 (0.88–2.81)	3.25** (1.53–6.91)	1.62 (0.88–2.97)	4.12** (1.76–9.66)

Ref. reference, EPTB extra-pulmonary tuberculosis, OR odds ratio, 95 % CI, 95 % confidence intervals
* p < .05, ** p < .01, *** p < .001
^aSuccess defined as cured and treatment completed
^bAdjusted for age, gender, type of TB and HIV

ISSN: 1471-2334