↓monocyte HLA-DR expression associated with secondary infection [2, 4]
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Variable monocyte HLA-DR expressiona
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HLA-DR expression correlates with TNFα production [24]
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No correlation between monocyte HLA-DR expression and TNFα production
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Correlation between monocyte HLA-DR and CD86 expression [6, 25]
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Correlation between monocyte HLA-DR and CD86 expression
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↓CD86 expression associated with increased severity of inflammation [7, 25]
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Widely variable monocyte CD86 expressiona
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Expansion of CD14loCD16hi monocyte population [26]
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Expansion of CD14loCD16hi monocyte population
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CD14loCD16hi monocytes major TNFα producers [11]
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‘Classical’ CD14hiCD16neg monocytes major TNFα producers
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