Fig. 2

Ingenuity Pathway Analysis for host proteins identified in the viral-enriched plasma fraction of patients with dengue. Pathway classification according to canonical pathways was performed using IPA software. The x-axis represents the pathways identified. The y-axis (left) shows the − log of the P-value calculated using Fisher’s exact test. The ratio (y-axis, right) represented by the line is calculated as follows: number of proteins in a given pathway that meet the cutoff criteria divided by total number of proteins that make up that pathway