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Table 6 Sensitivity, specificity, PPV and NPV for typhoid fever of WHO case definition

From: Evaluation of sensitivity and specificity of ELISA against Widal test for typhoid diagnosis in endemic population of Kathmandu

Suspected case of Typhoid fever

Sensitivity

Specificity

PPV

NPV

95 % CI

95 % CI

95 % CI

95 % CI

Isolation in Blood culture of;

S. typhi

76.81 %

99.22 %

97.07 %

92.71 %

71.99 % to 81.16 %

98.47 % to 99.66 %

94.31 % to 98.73 %

91.01 % to 94.18 %

Probable case of Typhoid fever

TH(1:160)

45.22 %

82.32 %

34.23 %

87.83 %

41.27 % to 49.17 %

79.91 % to 87.82 %

29.46 % to 38.96 %

81.59 % to 91.31 %

TO(1:80)

43.45 %

82.31 %

34.11 %

87.14 %

39.29 % to 48.97 %

78.96 % to 84.78 %

31.41 % to 38.85 %

83.72 % to 92.91 %