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Table 6 Sensitivity, specificity, PPV and NPV for typhoid fever of WHO case definition

From: Evaluation of sensitivity and specificity of ELISA against Widal test for typhoid diagnosis in endemic population of Kathmandu

Suspected case of Typhoid fever Sensitivity Specificity PPV NPV
95 % CI 95 % CI 95 % CI 95 % CI
Isolation in Blood culture of;
S. typhi 76.81 % 99.22 % 97.07 % 92.71 %
71.99 % to 81.16 % 98.47 % to 99.66 % 94.31 % to 98.73 % 91.01 % to 94.18 %
Probable case of Typhoid fever
TH(1:160) 45.22 % 82.32 % 34.23 % 87.83 %
41.27 % to 49.17 % 79.91 % to 87.82 % 29.46 % to 38.96 % 81.59 % to 91.31 %
TO(1:80) 43.45 % 82.31 % 34.11 % 87.14 %
39.29 % to 48.97 % 78.96 % to 84.78 % 31.41 % to 38.85 % 83.72 % to 92.91 %