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Table 6 Univariate and multivariate analyses of factors predicting recurrence-free survival of penicilliosis among HIV-negative patients

From: Differences in clinical characteristics and prognosis of Penicilliosis among HIV-negative patients with or without underlying disease in Southern China: a retrospective study

Factor

Univariate

Multivariate

HR

95 % CI

P

HR

95 % CI

P

Age > 60 or < 3 years

0.700

0.274–1.792

0.457

   

Underlying diseases

0.228

0.064–0.813

0.014*

0.289

0.074-1.132

0.075

Fever

0.300

0.065–1.378

0.122

   

Lymphadenopathy

2.074

0.601–7.155

0.249

   

Hepatomegaly

0.374

0.118–1.185

0.095

   

Splenomegaly

0.606

0.217–1.697

0.341

   

Cutaneous lesions

0.575

0.225–1.471

0.248

   

Cough

6.568

0.861–50.100

0.069

   

Dyspnoea

1.265

0.479–3.344

0.635

   

Anaemia

1.525

0.439–5.303

0.507

   

Osteolysis

0.581

0.209–1.618

0.299

   

Thoracalgia

1.204

0.453–3.200

0.710

   

Bloody stools/diarrhoea

1.122

0.326–3.869

0.855

   

Duration of diagnosis

1.026

0.405–2.597

0.957

   

WBC > 10*109/L

0.628

0.181–2.177

0.463

   

Neutrophils > 6.3*109/L

0.573

0.205–1.604

0.289

   

Lymphocytes < 1.10*109/L

2.093

0.730–6.004

0.169

   

Haemoglobin < 130 g/L

1.082

0.410–2.855

0.874

   

ALT > 45U/L

2.941

0.608–14.230

0.180

   

ALB < 55U/L

1.274

0.288–5.627

0.749

   

CD4 < 410/ul

1.003

0.998–1.008

0.289

   

CD8 < 190 /ul

0.994

0.985–1.002

0.146

   

CD4% < 31.98 %

3.033

1.186–7.754

0.015*

1.224

0.305–4.921

0.775

CD8% < 20.70 %

0.654

0.256–1.121

0.374

   

T cell% < 64.2 %

2.963

1.146–7.659

0.019*

1.950

0.504–7.539

0.333

IgG < 7 g/L

0.800

0.181–3.536

0.769

   

Chest imaging

0.708

0.251–1.999

0.515

   
  1. Patients with Penicillium marneffei infection were divided into two groups; Group D included patients with underlying disease, and Group ND included patients without underlying disease
  2. ALB serum albumin, ALT alanine aminotransferase, CI confidence interval, HR hazard ratio, WBC white blood cell, CD4 CD4 T cell count, CD8 CD8 T cell count, CD4% CD4 cell percentage, CD8% CD8 cell percentage, T cell% T lymphocyte cell percentage, IgG serum immunoglobulin G. *P < 0.05
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BMC Infectious Diseases

ISSN: 1471-2334

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