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Table 2 Performance of the molecular assays compared to culture

From: Performance evaluation of three commercial molecular assays for the detection of Mycobacterium tuberculosis from clinical specimens in a high TB-HIV-burden setting

Category Anyplex™ plus MTB/NTM/DR-TB GenoType MTBDRplus version 2.0 Xpert® MTB/RIF
Sensitivity (culture positive for MTB)
 Overall sensitivity (n = 55) 36 (65.5 %) 39 (70.9 %) 49 (89.1 %)
 Smear Positive (n = 23) 21 (91.3 %) 23 (100 %) 23 (100 %)
 Scanty Positive (n = 6) 3 (50 %) 4 (66.7) 5 (83.3 %)
 Smear negative (n = 26) 12 (46.2 %) 12 (46.2 %) 21 (80.8 %)*
Specificity
 Culture negative (n = 26) 25 (96.2 %) 24 (92.3 %) 26 (100 %)
  1. *P < 0.05 when Xpert® is compared to Anyplex™ plus and when Xpert® is compared to MTBDRplus