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Table 2 Performance of the molecular assays compared to culture

From: Performance evaluation of three commercial molecular assays for the detection of Mycobacterium tuberculosis from clinical specimens in a high TB-HIV-burden setting

Category

Anyplex™ plus MTB/NTM/DR-TB

GenoType MTBDRplus version 2.0

Xpert® MTB/RIF

Sensitivity (culture positive for MTB)

 Overall sensitivity (n = 55)

36 (65.5 %)

39 (70.9 %)

49 (89.1 %)

 Smear Positive (n = 23)

21 (91.3 %)

23 (100 %)

23 (100 %)

 Scanty Positive (n = 6)

3 (50 %)

4 (66.7)

5 (83.3 %)

 Smear negative (n = 26)

12 (46.2 %)

12 (46.2 %)

21 (80.8 %)*

Specificity

 Culture negative (n = 26)

25 (96.2 %)

24 (92.3 %)

26 (100 %)

  1. *P < 0.05 when Xpert® is compared to Anyplex™ plus and when Xpert® is compared to MTBDRplus