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Table 1 Frequency of different complications in fatal and non-fatal pertussis cases in different age groups in Brazil, 2007–2014. The rates displayed are the number of children with the specific complication/total number of children in each category (cured or fatal cases). Comparison of proportions was performed with the chi-square test

From: Increasing incidence of pertussis in Brazil: a retrospective study using surveillance data

   Complications
Age group   Pneumonia Encephalopathy Dehydration Otitis Malnutrition
0–2 months Cured cases 1237/6787 (18.2 %) 88/6763 (1.3 %) 159/6778 (2.3 %) 44/6748 (0.7 %) 71/6765 (1 %)
  Fatal cases 233/370 (63 %) 24/346 (6.9 %) 34/351 (9.7 %) 2/341 (0.6 %) 16/349 (4.6 %)
  p-Value <0.001 <0.001 <0.001 0.84 <0.001
3–6 months Cured cases 701/4550 (15.4 %) 49/4534 (1.1 %) 117/4533 (2.6 %) 64/4523 (1.4 %) 50/4526 (1.1 %)
  Fatal cases 57/83 (68.7 %) 9/78 (11.5 %) 10/79 (12.6 %) 2/78 (2.6 %) 4/78 (5.1 %)
  p-Value <0.001 <0.001 <0.001 0.39 0.006
7–15 months Cured cases 243/1764 (13.8 %) 14/1757 (0.8 %) 44/1758 (2.5 %) 46/1756 (2.6 %) 29/1758 (1.6 %)
  Fatal cases 13/21 (61.9 %) 1/19 (5.2 %) 0 1/20 (5 %) 0
  p-Value <0.001 0.39 - 0.96 -
16 months–4 years Cured cases 236/2612 (9 %) 15/2610 (0.6 %) 53/2615 (2 %) 51/2607 (2 %) 33/2609 (1.3 %)
  Fatal cases 3/10 (30 %) 0 0 0 2/10 (20 %)
  p-Value 0.08 - - - <0.001
5–14 years Cured cases 115/2557 (4.5 %) 9/2550 (0.3 %) 42/2558 (1.6 %) 64/2555 (2.5 %) 23/2551 (0.9 %)
  Fatal cases 1/4 (25 %) 1/4 (25 %) 0 0 0
  p-Value 0.44 <0.001 - - -
>15 years Cured cases 83/2152 (3.9 %) 5/2151 (0.2 %) 18/2154 (0.8 %) 38/2153 (1.8 %) 8/2152 (0.4 %)
  Fatal cases 1/4 (25 %) 0 0 0 1/4 (25 %)
  p-Value 0.37 - - - <0.001