Table 1 Overall mean health and cost outcomes for Canada
| Â | TIV | QIV | Difference (TIV vs. QIV) | % Difference |
|---|---|---|---|---|
Average influenza-related outcomes per season, n (95Â % CI) | ||||
Cases | 2,933,460 (2,532,276; 3,351,695) | 2,797,922 (2,392,853; 3,199,681) | −135,538 (−228,154; −76,677) | −4.6 (−7.7; −2.7) |
GP visits | 1,066,568 (921,034; 1,218,892) | 1,014,368 (868,298; 1,160,118) | −52,200 (−88,460; −29,055) | −4.9 (−8.2; −2.8) |
ER visits | 59,704 (51,257; 68,574) | 56,309 (47,987; 64,721) | −3,395 (−5,907; −1,731) | −5.7 (−9.7; −3.0) |
Hospitalizations | 32,986 (28,319; 37,886) | 31,110 (26,512; 35,757) | −1,876 (−3,264; −956) | −5.7 (−9.7; −3.0) |
Deaths | 4,836 (4,114; 5,606) | 4,508 (3,811; 5,230) | −328 (−584; −156) | −6.8 (−11.9; −3.2) |
Average costs per season, $ (95 % CI) | ||||
Vaccination | $114,269,815 (113,818,022; 114,795,606) | $153,621,770 (153,014,388; 154,328,631) | $39,351,954 (39,196,367; 39,533,025) | |
GP visits | $45,574,462 (39,355,763; 52,083,266) | $43,343,948 (37,102,387; 49,571,823) | -$2,230,514 (−3,779,889; −1,241,510) | |
ER visits | $13,337,288 (11,450,298; 15,318,666) | $12,578,851 (10,719,802; 14,457,926) | -$758,437 (−1,319,645; −386,684) | |
Hospitalization | $120,689,432 (103,441,040; 138,855,265) | $113,695,532 (96,748,864; 130,839,986) | -$6,993,900 (−12,204,664; −3,525,203) | |
Total payer costs | $293,870,997 (268,805,179; 320,376,234) | $323,240,101 (298,328,487; 348,108,942) | $29,369,104 (22,016,160; 34,131,5416) | |
Total costs, 2014–24: 5 % discounted, $ (95 % CI) | ||||
Vaccination | $868,017,693 (864,552,580; 872,000,633) | $1,166,943,465 (1,162,285,045; 1,172,298,039) | $298,925,772 (297,732,465; 300,297,407) | |
GP visits | $347,201,538 (298,121,148; 398,164,181) | $329,329,994 (280,856,904; 378,138,361) | $-17,871,544 (−29,416,959; −9,870,111) | |
ER visits | $101,255,332 (86,543,184; 116,554,469) | $95,274,727 (80,828,208; 109,823,373) | $-5,980,605 (−10,120,952; −3,025,115) | |
Hospitalization | $915,691,926 (781,948,765; 1,054,610,228) | $860,655,203 (728,830,865; 993,481,676) | $-55,036,723 (−93,315,528; −27,516,515) | |
Total payer costs | $2,232,166,489 (2,035,062,286; 2,436,875,507) | $2,452,203,389 (2,261,195,912; 2,649,106,709) | $220,036,899 (166,524,687; 257,670,736) | |
QALYs lost, n (95Â % CI) | ||||
Per season | 68,980 (59,036; 79,436) | 64,930 (55,206; 74,837) | −4,050 (−7,076; −2,033) | |
Total | 522,596 (446,330; 601,554) | 490,805 (414,820; 567,537) | −31,791 (−54,079; −15,845) | |
LYs lost, n (95Â % CI) | ||||
Per season | 45,675 (38,909; 52,852) | 42,732 (36,152; 49,573) | −2,944 (−5,215; −1,417) | |
Total | 344,912 (293,245; 398,169) | 322,013 (270,885; 374,069) | −22,899 (−39,878; −10,871) | |