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Table 5 Incidence rate ratios (IRR) for associated outcomes within a year following herpes zoster diagnosis

From: Incidence of herpes zoster and associated events including stroke—a population-based cohort study

 

CVD (excl. stroke)

Stroke

Sepsis

Bell’s palsy

 

n

IRRa (95 % CI)

n

IRRa (95 % CI)

n

IRRa (95 % CI)

n

IRRa (95 % CI)

All cases

64

1.82 (1.42–2.33)

111

1.34 (1.12–1.62)

37

1.47 (1.06–2.03)

71

10.6 (8.33–13.4)

Sex

        

Men

26

1.62 (1.10–2.38)

49

1.30 (0.98–1.72)

15

1.23 (0.74–2.05)

43

15.7 (11.6–21.3)

Women

38

1.99 (1.45–2.74)

62

1.38 (1.08–1.77)

22

1.68 (1.11–2.56)

28

6.99 (4.80–10.2)

p-value b

 

0.41

 

0.75

 

0.36

 

<0.01

Age (years)

        

0–39

0

.

4

10.3 (3.87–27.6)

3

9.10 (2.93–28.3)

15

23.4 (14.0–38.9)

40–49

1

1.15 (0.16–8.16)

0

.

3

9.42 (3.02–29.3)

1

2.62 (0.37–18.6)

50–59

12

3.51 (1.99–6.19)

2

0.44 (0.11–1.76)

0

.

6

7.23 (3.23–16.2)

60–69

21

2.68 (1.75–4.12)

13

1.12 (0.65–1.92)

3

0.79 (0.25–2.44)

17

9.09 (5.61–14.7)

70–79

16

1.37 (0.84–2.25)

35

1.47 (1.05–2.04)

6

0.79 (0.35–1.76)

13

7.69 (4.42–13.4)

80+

14

1.29 (0.76–2.18)

57

1.38 (1.07–1.80)

22

1.82 (1.19–2.77)

19

14.4 (9.03–23.0)

p-value c

 

0.06

 

<0.01

 

<0.01

 

0.01

  1. aAdjusted for age and sex
  2. bFrom Wald test of interaction between HZ and sex
  3. cFrom Wald test of interaction between HZ and age group