Fig. 2

Estimated annual incidence rate per 10,000 (extrapolated number) of norovirus-associated gastroenteritis cases in older adults living in high and upper-middle income countries^a. ^aPopulation based on 2013 World Bank estimate of 401,680,000 individuals aged ≥65 years in high (208,960,000) and upper-middle income (192,720,000) countries. ^bAnnual mortality rate estimates based on following sources: Hall et al. [51], Werber et al. [63], van Asten et al. [68]. ^cAnnual inpatient rate estimates based on following sources: Haustein et al. [69], Lopman et al. [70], van Asten et al. [68]. ^dAnnual outpatient rate estimates based on following sources: Gastanaduy et al. [45], Phillips et al. [42], van Asten et al. [68]. ^eAnnual case rate estimates based on following sources: Werber et al. [63], Bernard et al. [32]; if estimate accounts for incidence data published in de Wit et al. [94] which was published prior to the inclusion dates for this review, the upper incidence rate estimate would be 310 per 10,000 which corresponds to 12,452,080 estimated cases in high and upper middle income countries annually