The epidemiology of all-cause and rotavirus acute gastroenteritis and the characteristics of rotavirus circulating strains before and after rotavirus vaccine introduction in Yemen: analysis of hospital-based surveillance data

Table 3 Core study outcomes during pre & post-RV vaccination periods: binominal generalized linear models with probit link function

Pre & Post vaccination	Unadjusted Exponential (B)		Adjusted Exponential(B)^b
Periods N(%)	(95 % Wald CI)^a	P	(95 % Wald CI)^a	P
Treatment outcome
Successfully treated
Pre: 3547/3899 (90.9)	1		1
Post: 957/1161 (82.4)	0.640 (0.569–0.720)	0.0001	0.995 (0.808–1.227)	0.964
Referred for intensive care
Pre: 60/3899 (1.5)	1		1
Post: 8/1161 (0.7)	0.442 (0.295–0.660)	0.0001	0.615 (0.400–0.946)	0.027
Deaths
Pre 27/3899(0.7)	1		1
Post 13/1161 (1.12)	0.801 (0.526 -1.219)	0.299	0.772 (0.478–1.248)	0.291
Severe dehydrating diarrhea
Pre: 848/3902 (21.7)	1		1
Post: 168/1144 (14.7)	0.64 (0.54–0.77)	0.0001	0.501 (0.416–0.602)	0.0001
Rotavirus gastroenteritis
Pre: 1528/3676 (41.6)	1		1
Post: 233/1173 (19.9)	0.45 (0.38–0.51)	0.0001	0.523 (0.476–0.574)	0.0001

^aConfidence Interval
^bAdjusted for age group, gender, hospital site, symptoms duration(days), and diarrhea episodes duration(days)

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