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Table 3 Comparison of Clinical and laboratory characteristics between neonates with RSV and viruses other than RSV

From: Epidemiological and clinical profiles of respiratory syncytial virus infection in hospitalized neonates in Suzhou, China

Clinical Parameters

RSV- LRIs

Other viruses LRIs

P Value

 

n = 344

n = 131

 

Demographic data

   

Age (median, IQR)

17 (12–22)

17 (13–23)

0.002

Sex (male, %)

205 (59.6)

70 (53.4)

0.224

Birth weight (mean ± std, g)

3380.5 ± 460.6

3390.8 ± 471.1

0.820

Underlying condition (n, %)a

35 (10.2)

11 (8.4)

0.558

Clinical symptoms

   

Cough (n, %)

343 (99.7)

131 (98.5)

1.0

Fever (n, %)

75 (21.8)

46 (35.1)

0.003

Wheezing (n, %)

34 (9.9)

12 (9.2)

0.812

Tachypnea (n, %)

174 (50.6)

31 (23.7)

<0.001

Dyspnea (n, %)

68 (19.8)

17 (13.0)

0.084

Cyanosis (n, %)

18 (5.2)

8 (6.2)

0.708

Refusal to feed (n, %)

14 (4.1)

6 (4.6)

0.804

Physical examination

   

Moist rales (n, %)

267 (77.6)

72 (55.0)

<0.001

Wheezing rales (n, %)

34 (9.9)

12 (9.2)

0.812

Laboratory tests

   

White blood cells

9.1 ± 2.7

9.2 ± 3.0

0.777

C-reactive protein (median, IQR)

0.9 (0.3–2.6)

0.6 (0.1–2.1)

0.061

Alanine transarninase increase (n, %)

20 (5.8)

7 (5.3)

0.843

Creatine kinase-MB increase (n, %)

257 (74.7)

85 (64.9)

0.033

Abnormal chest X-ray (n, %)

307 (89.2)

67 (51.4)

<0.001

Theraphy

   

Supplemental oxygen (n, %)

59 (17.2)

11 (8.4)

0.016

Mechanical ventilation (n, %)

15 (4.3)

3 (2.3)

0.291

Duration of hospital days (median, IQR)

10 (9–12)

8 (7–10)

<0.001

  1. aUnderlying conditions: Congenital heart disease; Bronchopulmonary dysplasia; Bronchopulmonary malformation; Down Syndrome. RSV respiratory syncytial virus, LRI lower respiratory tract infection, IQR inter-quartile ranges