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Table 3 Comparison of Clinical and laboratory characteristics between neonates with RSV and viruses other than RSV

From: Epidemiological and clinical profiles of respiratory syncytial virus infection in hospitalized neonates in Suzhou, China

Clinical Parameters RSV- LRIs Other viruses LRIs P Value
  n = 344 n = 131  
Demographic data    
Age (median, IQR) 17 (12–22) 17 (13–23) 0.002
Sex (male, %) 205 (59.6) 70 (53.4) 0.224
Birth weight (mean ± std, g) 3380.5 ± 460.6 3390.8 ± 471.1 0.820
Underlying condition (n, %)a 35 (10.2) 11 (8.4) 0.558
Clinical symptoms    
Cough (n, %) 343 (99.7) 131 (98.5) 1.0
Fever (n, %) 75 (21.8) 46 (35.1) 0.003
Wheezing (n, %) 34 (9.9) 12 (9.2) 0.812
Tachypnea (n, %) 174 (50.6) 31 (23.7) <0.001
Dyspnea (n, %) 68 (19.8) 17 (13.0) 0.084
Cyanosis (n, %) 18 (5.2) 8 (6.2) 0.708
Refusal to feed (n, %) 14 (4.1) 6 (4.6) 0.804
Physical examination    
Moist rales (n, %) 267 (77.6) 72 (55.0) <0.001
Wheezing rales (n, %) 34 (9.9) 12 (9.2) 0.812
Laboratory tests    
White blood cells 9.1 ± 2.7 9.2 ± 3.0 0.777
C-reactive protein (median, IQR) 0.9 (0.3–2.6) 0.6 (0.1–2.1) 0.061
Alanine transarninase increase (n, %) 20 (5.8) 7 (5.3) 0.843
Creatine kinase-MB increase (n, %) 257 (74.7) 85 (64.9) 0.033
Abnormal chest X-ray (n, %) 307 (89.2) 67 (51.4) <0.001
Theraphy    
Supplemental oxygen (n, %) 59 (17.2) 11 (8.4) 0.016
Mechanical ventilation (n, %) 15 (4.3) 3 (2.3) 0.291
Duration of hospital days (median, IQR) 10 (9–12) 8 (7–10) <0.001
  1. aUnderlying conditions: Congenital heart disease; Bronchopulmonary dysplasia; Bronchopulmonary malformation; Down Syndrome. RSV respiratory syncytial virus, LRI lower respiratory tract infection, IQR inter-quartile ranges