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Table 3 Regression analyses. Univariate and multivariate logistic regression analysis of baseline characteristic, clinical and laboratory parameters for development of severe dengue according to the WHO’s 2009 definition among 153 hospitalized adults with dengue

From: Identification of clinical factors associated with severe dengue among Thai adults: a prospective study

Characteristics Univariate logistic regression analysis Multivariate logistic regression analysis
  Odds ratio (95 % CI) p-value Odds ratio (95 % CI) p-value
Age     
  ≤ 40 years 1.000 (Reference)   1.000 (Reference)  
  > 40 years 4.461 (1.655–12.023) 0.003 5.215 (1.538–17.689) 0.008
NSAIDs or COX II inhibitors     
 No 1.000 (Reference)    
 Yes 3.662 (1.211–11.070) 0.021   
Persistent vomiting     
 No 1.000 (Reference)   1.000 (Reference)  
 Yes 5.850 (2.114–16.187) 0.001 4.817 (1.375–16.873) 0.014
Absolute lymphocytes     
  ≤ 2000 cells per μL 1.000 (Reference)    
  > 2000 cells per μL 3.812 (1.156–12.574) 0.028   
Absolute atypical lymphocytes     
  ≤ 300 cells per μL 1.000 (Reference)   1.000 (Reference)  
  > 300 cells per μL 4.875 (1.858–12.794) 0.001 3.163 (1.017–9.834) 0.047
Lactate level     
  < 2.0 mmol/L 1.000 (Reference)   1.000 (Reference)  
  ≥ 2.0 mmol/L 10.571 (3.811–29.321) <0.001 7.340 (2.334–23.087) 0.001
  1. Abbreviations: CI confidence interval, NSAIDs nonsteroidal anti-inflammatory drugs, COX II cyclooxygenase II