Table 3 Regression analyses. Univariate and multivariate logistic regression analysis of baseline characteristic, clinical and laboratory parameters for development of severe dengue according to the WHO’s 2009 definition among 153 hospitalized adults with dengue
Characteristics | Univariate logistic regression analysis | Multivariate logistic regression analysis | ||
|---|---|---|---|---|
| Â | Odds ratio (95Â % CI) | p-value | Odds ratio (95Â % CI) | p-value |
Age | Â | Â | Â | Â |
  ≤ 40 years | 1.000 (Reference) |  | 1.000 (Reference) |  |
  > 40 years | 4.461 (1.655–12.023) | 0.003 | 5.215 (1.538–17.689) | 0.008 |
NSAIDs or COX II inhibitors | Â | Â | Â | Â |
 No | 1.000 (Reference) |  |  |  |
 Yes | 3.662 (1.211–11.070) | 0.021 |  |  |
Persistent vomiting | Â | Â | Â | Â |
 No | 1.000 (Reference) |  | 1.000 (Reference) |  |
 Yes | 5.850 (2.114–16.187) | 0.001 | 4.817 (1.375–16.873) | 0.014 |
Absolute lymphocytes | Â | Â | Â | Â |
  ≤ 2000 cells per μL | 1.000 (Reference) |  |  |  |
  > 2000 cells per μL | 3.812 (1.156–12.574) | 0.028 |  |  |
Absolute atypical lymphocytes | Â | Â | Â | Â |
  ≤ 300 cells per μL | 1.000 (Reference) |  | 1.000 (Reference) |  |
  > 300 cells per μL | 4.875 (1.858–12.794) | 0.001 | 3.163 (1.017–9.834) | 0.047 |
Lactate level | Â | Â | Â | Â |
  < 2.0 mmol/L | 1.000 (Reference) |  | 1.000 (Reference) |  |
  ≥ 2.0 mmol/L | 10.571 (3.811–29.321) | <0.001 | 7.340 (2.334–23.087) | 0.001 |