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Table 3 Resistance and decreased susceptibility to cefixime (CFM) or ceftriaxone (CRO) in Neisseria gonorrhoeae isolates cultured from 1995 to 2005 in Kanagawa area, Japan

From: Emergence and evolution of internationally disseminated cephalosporin-resistant Neisseria gonorrhoeae clones from 1995 to 2005 in Japan

Year

Number of isolatesa

CFM-DSa,b

CFM-Ra,c

CRO-DSa,b

  

No.a

%

No.a

%

No.a

%

1995

34 (1)

1 (1)

2.9

1 (0)

2.9

0

0

1996

70 (0)

0

0

0

0

0

0

1997

88 (1)

0

0

1 (1)

1.1

0

0

1998

89 (84)

0

0

5 (5)

5.6

0

0

1999

69 (50)

2 (2)

2.9

3 (3)

4.3

0

0

2000

54 (49)

6 (5)

11.1

6 (5)

11.1

1 (1)

1.9

2001

102 (90)

10 (9)

9.8

34 (32)

33.3

17 (17)

16.7

2002

21 (21)

0

0

12 (12)

57.1

4 (4)

19.0

2003

55 (27)

5 (4)

9.1

26 (23)

47.3

16 (14)

29.1

2004

74 (34)

10 (10)

13.5

29 (24)

39.2

16 (13)

21.6

2005

34 (15)

8 (6)

23.5

10 (9)

29.4

5 (5)

14.7

  1. aNumber of isolates examined genetically is given in parentheses
  2. bMIC = 0.125 mg/L of cefixime or ceftriaxone
  3. cMIC > 0.125 mg/L of cefixime