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Table 4 Characteristics of the patients according to the carrier status of extended-spectrum beta-lactamase (ESBL) Enterobacteriaceae

From: First multicenter study on multidrug resistant bacteria carriage in Chinese ICUs

Characteristics ESBL-Enterobacteriaceae carriage
  On admission ICU-acquired Not carrier P value *
  n (%) n (%) n (%)  
Total 224 (100.0) 69 (100.0) 393 (100.0)  
Male (yes) 137 (61.2) 45 (65.2) 223 (56.7) 0.19
Severe/critical status on admission 172 (76.8) 53 (76.8) 300 (76.3) 1.0
Previous hospitalization 111 (49.6) 36 (52.2) 145 (36.9) 0.02
Origin of patients before ICUa
- community 10 (4.5) 4 (5.8) 14 (3.6) reference
- emergency room 38 (17.0) 17 (24.6) 60 (15.3) 1.0
- other wards 155 (69.2) 42 (60.9) 297 (75.6) 0.27
- other hospitals 12 (5.4) 4 (5.8) 14 (3.6) 1.0
- others/no data 7 (3.1) 2 (2.9) 7 (1.8) 1.0
Invasive devices before ICU 117 (52.2) 29 (42.0) 167 (42.5) 0.94
Invasive devices in ICU 212 (94.6) 67 (97.1) 361 (91.9) 0.12
- mechanical ventilation 119 (53.1) 41 (59.4) 221 (56.2) 0.62
- indwelling urinary catheter 202 (90.2) 64 (92.8) 363 (92.4) 0.91
- intravascular catheter 182 (81.3) 56 (81.2) 276 (70.2) 0.06
Antibiotic in the last 3 months 104 (46.4) 37 (53.6) 138 (35.1) 0.003
Antibiotic on ICU admission 185 (82.6) 59 (85.5) 342 (87.2) 0.69
- > 1 drug 72 (32.1) 23 (33.3) 137 (34.9) 0.89
Antibiotic in ICU
- none 16 (7.1) 3 (4.4) 16 (4.1) reference
- 1 drug 98 (43.8) 27 (39.1) 189 (48.1) 0.72
- 2 drugs 64 (28.6) 19 (27.5) 125 (31.8) 0.72
- > 2 drugs (3–7) 46 (20.5) 20 (29.0) 63 (16.0) 0.55
- penicillins 3 (1.3) 2 (2.9) 5 (1.3) 0.31
- penicillins + inhibitors 62 (27.7) 27 (39.1) 104 (26.5) 0.03
- cephalosporins 1st & 2nd G 45 (20.1) 7 (10.1) 103 (26.2) 0.004
- cephalosporins 3rd G /aztreonam 75 (33.5) 28 (40.6) 122 (31.0) 0.12
- carbapenems 54 (24.1) 20 (29.0) 66 (16.8) 0.02
- aminoglycosides 4 (1.8) 1 (1.5) 8 (2.0) 1.0
- fluoroquinolones 41 (18.3) 8 (11.6) 66 (16.8) 0.28
- glycopeptides 39 (17.4) 17 (24.6) 60 (15.3) 0.05
- others 159 (71.0) 17 (24.6) 117 (29.8) 0.39
Type of discharge at 28 ICU daysb
- discharged from hospital 31 (13.8) 10 (14.5) 42 (10.7) reference
- remain in ICU 16 (7.1) 10 (14.5) 10 (2.5) 0.02
- other ward 161 (71.9) 40 (58.0) 315 (80.2) 0.11
- death 15 (6.7) 5 (7.2) 25 (6.4) 1.0
  Median (range) Median (range) Median (range)  
Age (year) 65 (9 – 91) 64 (22–95) 67 (15–94) 0.60
Length of stay (days)
- in hospital before ICU admission 7 (0 – >60) 5 (0 – >60) 6 (0 – >60) 0.77
- in ICU 4 (1 – >28) 8 (2 – >28) 4 (1 – >28) <0.001
- before MDR acquisition 7 (3–28)  
Total antibiotic-days in ICU 3 (0–28) 4 (0–19) 3 (0–25) <0.001
  1. *Comparing ICU-acquired MDRO patients to non carriers; aData are missing for 3 patients; bData are missing for 6 patients