High incidence of diagnosis with syphilis co-infection among men who have sex with men in an HIV cohort in Ontario, Canada

Table 2 Rates of new syphilis among HIV-positive MSM in the OCS compared to males in Ontario

	HIV-positive MSM, OHTN Cohort Study (OCS)				Ontario males (a)
Year	Rate of first diagnosis per 100PY (95 % CI)	Rate of re-diagnosis per 100PY (95 % CI) (b)	Rate of any new diagnosis per 100PY (95 % CI)	Percent change from preceding year	Rate of new infectious syphilis case per 100PY	Percent change from preceding year
2006	1.2 (0.6, 2.5)	4.0 (1.9, 8.4)	1.8 (1.1, 3.0)	---	0.0055	---
2007	1.7 (1.1, 2.7)	3.2 (1.8, 5.8)	2.1 (1.5, 2.9)	13.2	0.0061	10.9
2008	1.4 (0.9, 2.1)	6.7 (4.6, 9.8)	2.6 (1.9, 3.4)	24.3	0.0065	6.6
2009	3.3 (2.5, 4.4)	9.0 (6.6, 12.3)	4.7 (3.8, 5.8)	82.8	0.0107	64.6
2010	2.0 (1.4, 2.9)	10.9 (8.3, 14.4)	4.3 (3.5, 5.4)	−7.9	0.0112	4.7

PY Person-years, CI Confidence interval
(a) Population-based rates of reported infectious syphilis among males in Ontario, Canada. Source: [20]
(b) Re-diagnosis defined as an observable four-fold rise in RPR titre. See text for details

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