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Table 2 Diagnostic accuracy results of overall NS1 Ag-based test kits

From: Evaluation of the diagnostic accuracy of nonstructural protein 1 Ag-based tests for dengue virus in Asian population: a meta-analysis

  No. of study Sensitivity % Specificity % Heterogeneity %
(95 % CI) (95 % CI) (I2)
Overall 18 66 (64.5–67.5) 97.9 (97.3–100) 82.6
Serological status
 Primary 9 88 (85.8–89.9)   89.2
 Secondary 10 60.8 (57.8–63.8)   93.2
DENV serotypes
 DENV-1 10 79.5 (76.6–82.3)   81
 DENV-2 11 62.7 (59.1–66.2)   84.2
 DENV-3 10 73 (69.2–76.6)   79.5
 DENV-4 5 46 (36–59.3)   56
Clinical severity
 Dengue Fever 5 70.3 (66.1–74.2)   80.8
 Dengue Hemorrhagic Fever 5 58.8 (54–63.4)   71.6
NS1 test assays
 ELISA 14 63.3 (61.5–65.1)   94.9
 IC 7 72.9 (70.1–75.5)   90.8