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Table 4 Base case and sensitivity analysis results

From: The health and economic impact of vaccination with 7-valent pneumococcal vaccine (PCV7) during an annual influenza epidemic and influenza pandemic in China

Parameter

Value

Deaths Averted

Life Years Saved (Millions)

Cost (Savings) (Billions)

Cost Per Life Year Saved

Non-Pandemic

     

  Base Case

 

76714

2.50

30.67

12281 (US$1899)

Vaccine Coverage

     

  Low

75 %

76209

2.46

24.75

10072 (US$1558)

  High

95 %

77220

2.54

36.85

14525 (US$2247)

Vaccine Price

     

  Low (-10 %)

774

76714

2.50

26.40

10572 (US$1635)

  High (+10 %)

946

76714

2.50

34.94

13991 (US$2164)

Herd Effect

     

  Reduced by 50 %

 

41195

1.47

36.17

24549 (US$3797)

Disease Incidence

     

  Low (-10 %)

 

69167

2.25

31.90

14158 (US$2190)

  High (+10 %)

 

84524

2.75

29.40

10676 (US$1651)

Case Fatality Rate

     

  Low (-10 %)

 

69063

2.25

30.67

13640 (US$2109)

  High (+10 %)

 

84411

2.75

30.67

11160 (US$1726)

Pandemic

     

  Base Case

 

707526

34.43

(41.03)

Dominant

Vaccine Coverage

     

  Low

75 %

702582

34.03

(46.88)

Dominant

  High

95 %

712470

34.82

(34.93)

Dominant

Vaccine Price

     

  Low (-10 %)

774

707526

34.43

(45.30)

Dominant

  High (+10 %)

946

707526

34.43

(36.76)

Dominant

Herd Effect

     

  Reduced by 50 %

 

384613

19.65

(0.48)

Dominant

Disease Incidence

     

  Low (-10 %)

 

641668

31.23

(33.21)

Dominant

  High (+10 %)

 

782365

38.09

(50.06)

Dominant

Case Fatality Rate

     

  Low (-10 %)

 

637577

31.02

(41.03)

Dominant

  High (+10 %)

 

779261

37.92

(41.03)

Dominant

  1. All values measured in 2011 Chinese Yuan
  2. July 2011 exchange rate, US$ = ¥6.465 [11]