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Table 3 Reduction in prevalence of carriage with the Conjugate C vaccine

From: The impact of aggregating serogroups in dynamic models of Neisseria meningitidis transmission

Vaccine Program

Model Type

Serogroup

t = 149

t = 160

t = 175

t = 190

Relative Change

1

2-strain model

C

0.005

0.003

0.000

0.000

−0.760

 

(0.012)

(0.007)

(0.000)

(0.000)

(0.427)

Other

0.109

0.108

0.107

0.108

−0.009

 

(0.008)

(0.008)

(0.010)

(0.009)

(0.054)

Total

0.115

0.111

0.107

0.108

−0.050

 

(0.020)

(0.015)

(0.011)

(0.009)

(0.068)

4-strain model

B

0.031

0.030

0.031

0.031

0.014

 

(0.013)

(0.010)

(0.012)

(0.014)

(0.276)

C

0.013

0.008

0.000

0.000

−0.960

 

(0.012)

(0.008)

(0.001)

(0.000)

(0.196)

Other

0.045

0.047

0.050

0.050

0.357

 

(0.028)

(0.026)

(0.021)

(0.022)

(0.860)

 Nl

0.025

0.025

0.025

0.025

−0.011

 

(0.003)

(0.002)

(0.002)

(0.004)

(0.082)

Total

0.114

0.110

0.106

0.106

−0.070

 

(0.056)

(0.047)

(0.036)

(0.039)

(0.102)

2

2-strain model

C

0.006

0.002

0.000

0.000

−0.840

 

(0.011)

(0.004)

(0.000)

(0.000)

(0.367)

Other

0.108

0.110

0.108

0.107

−0.007

 

(0.011)

(0.009)

(0.009)

(0.009)

(0.058)

Total

0.114

0.112

0.108

0.107

−0.053

 

(0.022)

(0.013)

(0.010)

(0.009)

(0.073)

4-strain model

B

0.031

0.031

0.031

0.032

0.064

 

(0.015)

(0.012)

(0.013)

(0.012)

(0.259)

C

0.015

0.006

0.000

0.000

−1.00

 

(0.014)

(0.006)

(0.001)

(0.000)

(0.000)

Other

0.047

0.050

0.051

0.052

0.412

 

(0.030)

(0.027)

(0.022)

(0.020)

(1.643)

Nl

0.026

0.025

0.025

0.025

−0.014

 

(0.003)

(0.002)

(0.003)

(0.003)

(0.078)

Total

0.118

0.112

0.107

0.108

−0.076

 

(0.061)

(0.047)

(0.038)

(0.035)

(0.097)

3

2-strain model

C

0.007

0.001

0.000

0.000

−0.840

 

(0.012)

(0.002)

(0.000)

(0.000)

(0.367)

Other

0.109

0.110

0.108

0.108

−0.007

 

(0.011)

(0.030)

(0.010)

(0.010)

(0.060)

Total

0.116

0.111

0.108

0.108

−0.063

 

(0.022)

(0.032)

(0.010)

(0.010)

(0.087)

4-strain model

B

0.031

0.034

0.032

0.031

0.064

 

(0.015)

(0.017)

(0.016)

(0.013)

(0.259)

C

0.014

0.004

0.000

0.000

−1.00

 

(0.010)

(0.007)

(0.001)

(0.000)

(0.000)

Other

0.046

0.044

0.048

0.052

0.412

 

(0.024)

(0.027)

(0.022)

(0.020)

(−0.004)

Nl

0.025

0.025

0.025

0.025

−0.014

 

(0.002)

(0.003)

(0.002)

(0.003)

(0.078)

Total

0.115

0.108

0.105

0.108

−0.061

 

(0.052)

(0.054)

(0.040)

(0.036)

(0.103)

  1. Reduction in the prevalence of carriage when an immunization program with the Conjugate C Vaccine is scheduled at 12 month (program 1), 12 years (program 2), and both 12 months and 12 years (program 3) beginning at t = 150 years. Results for both 2-strain and 4-strain models are shown