Table 2 Demographic characteristics of patients with TBM and healthy controls

Number of cases

17

17

Sex (n = male/female)

13 / 4

13 / 4

Age (years)

50.76 ± 18.97

50.41 ± 17.20

0.153

0.698

Education (years)

9.18 ± 5.11

13.18 ± 4.91

0.291

0.594

Total intracranial volume (TIV) (cm³)

1491.16 ± 120.01

1572.95 ± 115.23

0.099

0.755

 Gray matter (GM)

676.41 ± 55.64

717.43 ± 50.31

0.579

0.452

 White matter (WM)

495.33 ± 46.12

528.74 ± 35.04

0.676

0.417

 Cerebrospinal fluid (CSF)

319.42 ± 34.31

326.79 ± 40.71

1.415

0.243

WAIS

 Picture Completion

7.18 ± 3.49

11.71 ± 4.37

4.126

0.051

 Vocabulary

8.82 ± 3.38

12.12 ± 2.93

2.786

0.106

 Digit Symbol

7.00 ± 3.03

12.12 ± 3.10

14.130

0.001*

 Similarities

7.59 ± 3.32

11.53 ± 3.04

4.917

0.035*

 Block Design

8.29 ± 2.95

11.82 ± 3.19

4.988

0.033*

 Arithmetic

8.06 ± 2.84

11.12 ± 2.40

4.139

0.051*

 Matrix Reasoning

8.12 ± 3.92

11.71 ± 2.93

4.334

0.046*

 Digit Span

8.50 ± 3.98

11.35 ± 3.06

1.683

0.205

 Information

8.18 ± 2.46

11.41 ± 3.54

2.122

0.156

 Picture Arrangement

7.62 ± 3.46

11.47 ± 4.20

3.359

0.077*

 Comprehension

8.65 ± 3.43

12.35 ± 3.30

2.997

0.094

 Letter-Number Sequencing

6.40 ± 4.22

10.43 ± 3.76

4.501

0.044

 Verbal comprehension (VCI)

90.24 ± 14.71

108.82 ± 16.22

4.258

0.048*

 Perceptual organization (POI)

87.53 ± 18.45

111.29 ± 19.49

6.009

0.020*

 Working memory (WMI)

85.25 ± 18.48

105.06 ± 16.78

4.829

0.036*