Table 2 Incidence density rates of malaria per 100 child-years of follow-up in the 1117 HIV-infected children included in the pWADA cohort, Abidjan, May-August 2012
Characteristics | N | Number of child-years of follow-up | Incidence density rate with 95 % Confidence Interval for all cases of malaria: probable, confirmed including recurrences | Incidence density rate with 95 % Confidence Interval for confirmed malaria including recurrences | ||||
|---|---|---|---|---|---|---|---|---|
n (%) | Incidence density rate (per 100 child-years) | (95 % Confidence Interval) | n’ (%) | Incidence density rate (per 100 child-years) | (95 % Confidence Interval) | |||
Incidence density rate of malaria | ||||||||
Cases without recurrences | 1117 | 278 | 48 (94.1) | 17.2 | (12.4-22.1) | - | - | - |
Recurrence cases | 1117 | 278 | 3 (5.9) | 1.1 | (0.0-2.3) | - | - | - |
Confirmed | 1117 | 278 | 28 (55.0) | 10.1 | (6.3-13.8) | - | - | - |
Probable | 1117 | 278 | 23 (45.0) | 8.3 | (4.9-11.6) | - | - | - |
Overall (confirmed and probable) | 51 (100.0) | 18.3 | (13.3-23.4) | - | - | - | ||
1117 | 278 | |||||||
Incidence density rate of malaria according to treatment | ||||||||
On ART – On Cotrimoxazole | 667 | 166 | 7 (13.7) | 4.2 | (1.1-7.3) | 4 (14.3) | 2.4 | (0.0-4.8) |
Off ART – On Cotrimoxazole | 83 | 21 | 3 (5.9) | 14.5 | (0.0-30.9) | 2 (7.1) | 9.7 | (0.0-23.1) |
On ART – Off Cotrimoxazole | 323 | 80 | 36 (70.6) | 44.7 | (30.1-59.3) | 19 (67.9) | 23.6 | (13.0-34.2) |
Off ART – Off Cotrimoxazole | 35 | 9 | 5 (9.8) | 57.3 | (7.1-107.6) | 3 (10.7) | 34.4 | (0.0-73.3) |
Immunodeficiency according to age a | ||||||||
Severe | 69 | 17 | 5 (9.8) | 29.4 | (3.61-55.2) | 3 (10.7) | 17.5 | (0.0-37.2) |
Moderate | 106 | 26 | 6 (11.8) | 23.1 | (4.6-41.5) | 4 (14.3) | 15.1 | (0.3-30.0) |
No/Missing | 942 | 235 | 40 (78.4) | 17.0 | (11.7-22.3) | 21 (75.0) | 8.9 | (5.1-12.8) |
Age | ||||||||
<5 years | 144 | 36 | 11 (21.6) | 30.7 | (12.5-48.8) | 6 (21.4) | 16.7 | (3.3-30.1) |
[5-10[years | 443 | 110 | 20 (39.2) | 18.1 | (10.2-26.1) | 12 (42.9) | 10.9 | (4.7-17.0) |
≥10 years | 530 | 132 | 20 (39.2) | 15.1 | (8.5-21.8) | 10 (35.7) | 7.6 | (2.9-12.3) |
Centres | ||||||||
University hospital of Cocody | 182 | 45 | 1 (2.0) | 2.2 | (0.0-6.5) | 1 (3.6) | 2.2 | (0.0-6.5) |
University hospital of Yopougon | 344 | 86 | 9 (17.6) | 10.5 | (3.6-17.4) | 4 (14.3) | 4.7 | (0.1-9.2) |
CePReF | 322 | 80 | 23 (45.1) | 28.7 | (17.0-40.4) | 11 (39.3) | 13.7 | (5.6-21.8) |
CIRBA | 212 | 53 | 7 (13.7) | 13.3 | (3.4-23.1) | 2 (7.1) | 3.8 | (0.0-9.0) |
MTCT-Plus | 57 | 14 | 11 (21.6) | 77.5 | (31.7-123.2) | 10 (35.7) | 70.4 | (26.8-114.1) |